High-sensitivity fiber-optic interferometric refractive index sensors (FIRSs) have been of interest to researchers due to their potential to fabricate specific physical, chemical, and biological sensors. Fabricating interferometers working near the dispersion turning point (DTP) is an effective approach to improve the sensitivity of FIRSs. However, the group effective refractive index (RI) difference approaching 0 and the ratio of the variation of the effective RI difference to the external RI change being −1 cannot be simultaneously realized in low RI sensing, which restricts the further improvement of sensing sensitivity. Here, dual-path Mach-Zehnder interferometers (MZIs) with unequal geometrical path length are proposed for ultrasensitive RI sensing. The dual-path MZIs contain fiber path and sample path of different geometrical lengths to form the optical path difference. The dual-path MZIs can not only show a turning point where the sensing sensitivity tends to be infinite, which is similar to the previously reported DTP, but also get the constant value −1 for the RI response factor, leading to the result that the dips within an over-500-nm band width around the turning point can achieve high sensitivity reaching 10 5 nm/RIU level or higher. Ultrahigh sensitivity of −1.26 × 10 6 nm/RIU has been experimentally demonstrated at the RI around 1.35022. The dual-path MZIs proposed here may enlighten new ideas for developing high-sensitivity FIRSs.