Ultra-miniaturized glucose biosensor using zinc oxide nanorod-based field effect transistor

Zong, Ximei; Zhang, Zhizhong; Zhu, Rong

doi:10.1109/icsens.2017.8234339

Cited by 5 publications

(2 citation statements)

References 11 publications

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“…Although this device is promising and shows stability in vitro , the in-vivo test was halted after only 4 days of the planned six due to biofouling, displaying a shorter lifetime. Another device using a zinc oxide nanorod-based field effect transistor also aimed to be minimally invasive by reducing its sensing area to 180 μm^2 and an extremely low detection limit of 1 µM but at the price of a much lower sensitivity of 1.6 mA mM −1 cm −2 ( Zong et al, 2017 ). With a similar aim to reduce the pain and invasiveness that accompany current CGMs, all the while maintaining acceptable levels of sensitivity and reliability, a study used the microneedles to increase skin permeability and glucose across allowing for transdermal glucose to be used more effectively ( Brown et al, 2018 ).…”

Section: Continuous Monitoring Of Glucose In Different Body Fluidsmentioning

confidence: 99%

Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables

Johnston

Wang

et al. 2021

Front. Bioeng. Biotechnol.

104

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Continuous glucose monitors (CGMs) for the non-invasive monitoring of diabetes are constantly being developed and improved. Although there are multiple biosensing platforms for monitoring glucose available on the market, there is still a strong need to enhance their precision, repeatability, wearability, and accessibility to end-users. Biosensing technologies are being increasingly explored that use different bodily fluids such as sweat and tear fluid, etc., that can be calibrated to and therefore used to measure blood glucose concentrations accurately. To improve the wearability of these devices, exploring different fluids as testing mediums is essential and opens the door to various implants and wearables that in turn have the potential to be less inhibiting to the wearer. Recent developments have surfaced in the form of contact lenses or mouthguards for instance. Challenges still present themselves in the form of sensitivity, especially at very high or low glucose concentrations, which is critical for a diabetic person to monitor. This review summarises advances in wearable glucose biosensors over the past 5 years, comparing the different types as well as the fluid they use to detect glucose, including the CGMs currently available on the market. Perspectives on the development of wearables for glucose biosensing are discussed.

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Section: Continuous Monitoring Of Glucose In Different Body Fluidsmentioning

confidence: 99%

Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables

Johnston

Wang

et al. 2021

Front. Bioeng. Biotechnol.

104

View full text Add to dashboard Cite

show abstract

“…Recent advances in microsensing techniques are leading to a growing need for on-chip electronic instrumentation, not only providing the required performances but also simultaneously complying with the constraints of low power and compact size, to fully satisfy the emerging market demands and potential applications of portable and wearable sensing devices. New transduction techniques in micro-integrated sensors include resonant detection and complex impedance characterization, as in surface acoustic wave sensors [ 1 ], gas sensors [ 2 , 3 , 4 , 5 ], laser interferometry [ 6 ], brain monitoring [ 7 ], non-invasive light detection [ 8 ] or biological impedance measurement [ 9 , 10 ]. For these transducers, a suitable interrogation approach, which presents advantages compared to other electronic readout techniques due to its characteristics, is synchronous demodulation.…”

Section: Introductionmentioning

confidence: 99%

A CMOS Self-Contained Quadrature Signal Generator for SoC Impedance Spectroscopy

Márquez

Pérez-Bailón

Calvo

et al. 2018

Sensors

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This paper presents a low-power fully integrated quadrature signal generator for system-on-chip (SoC) impedance spectroscopy applications. It has been designed in a 0.18 μm-1.8 V CMOS technology as a self-contained oscillator, without the need for an external reference clock. The frequency can be digitally tuned from 10 to 345 kHz with 12-bit accuracy and a relative mean error below 1.7%, thus supporting a wide range of impedance sensing applications. The proposal is experimentally validated in two impedance spectrometry examples, achieving good magnitude and phase recovery results compared to the results obtained using a commercial LCR-meter. Besides the wide frequency tuning range, the proposed programmable oscillator features a total power consumption lower than 0.77 mW and an active area of 0.129 mm2, thus constituting a highly suitable choice as stimulation module for instrument-on-a-chip devices.

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Design of a Plasmonic Sensor Using Inter-coupled Gold Nanorods for Glucose Detection in Urine

Naznin,

Sher

2024

Plasmonics

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Ultra-miniaturized glucose biosensor using zinc oxide nanorod-based field effect transistor

Cited by 5 publications

References 11 publications

Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables

Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables

A CMOS Self-Contained Quadrature Signal Generator for SoC Impedance Spectroscopy

Design of a Plasmonic Sensor Using Inter-coupled Gold Nanorods for Glucose Detection in Urine

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