2017
DOI: 10.1038/srep44770
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Ultra-wide range field-dependent measurements of the relaxivity of Gd1−xEuxVO4 nanoparticle contrast agents using a mechanical sample-shuttling relaxometer

Abstract: The current trend for Magnetic Resonance Imaging points towards higher magnetic fields. Even though sensitivity and resolution are increased in stronger fields, T1 contrast is often reduced, and this represents a challenge for contrast agent design. Field-dependent measurements of relaxivity are thus important to characterize contrast agents. At present, the field-dependent curves of relaxivity are usually carried out in the field range of 0 T to 2 T, using fast field cycling relaxometers. Here, we employ a hi… Show more

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Cited by 23 publications
(18 citation statements)
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“…With the availability of a commercial electronic FC relaxometer since 1997, NMR relaxometry received new momentum, as it is now routinely possible to measure R 1 ( ω ) in a frequency range of 10 kHz<ω/(2π)<30 MHz ( 1 H). Taking recourse to home‐built instruments and compensating for the earth field, frequencies down to 100 Hz and recently even down to 3 Hz are accessible …”
Section: Introductionmentioning
confidence: 99%
“…With the availability of a commercial electronic FC relaxometer since 1997, NMR relaxometry received new momentum, as it is now routinely possible to measure R 1 ( ω ) in a frequency range of 10 kHz<ω/(2π)<30 MHz ( 1 H). Taking recourse to home‐built instruments and compensating for the earth field, frequencies down to 100 Hz and recently even down to 3 Hz are accessible …”
Section: Introductionmentioning
confidence: 99%
“…Similarly, an experiment by Chou et al measured the relaxivity (r1) of paramagnetic contrast agents over a large range of field strengths (0–12 T), revealing a Lorentzian shape (reproduced in Fig. S3a in the Supplemental Material) 24 . However, when only examined between the range of 1.5–8.45 T, the measurements by Chou et al (provided in Fig.…”
Section: Methodsmentioning
confidence: 73%
“…Lanthanide-ion doped (Ln 3+ ) inorganic luminescent phosphors are an important class of optical materials and find application in a variety of fields ranging from optical thermometers 1,2 , light emitting diodes [3][4][5] , lasers 6,7 , anti-counterfeiting 8 , and optical sensors 9 to markers for plastic recycling 10 or bio-imaging [11][12][13] . Nevertheless, luminescence in most inorganic phosphors is marred by an overall-low emission intensity.…”
Section: Introductionmentioning
confidence: 99%