Ultrafast voltammetric determination of biological thiols on the copper nanodoped mercury monolayer carbon fiber electrode

Fast cyclic voltammetry of redox system NAD+/NADH on the copper nanodoped mercury monolayer carbon fiber electrode

“…This procedure was realized as reported previously [8]. For the analytical signal (AS) we have used the peak current density (j p ) and the peak electric charge (Q p ).…”

“…As a result, the electrocatalytic process of systems where Cu 2+ acts as a catalyst on a nanostructured Cu-MMCFE ( Fig. 1) occurs very fast (diffusionless conditions) which assures a picomolar sensitivity for Cu 2+ determination [10] as well as for the biosystems whose redox transformation are catalyzed by Cu 2+ [8,9] under conditions where fast cyclic voltammetry is applied.…”

“…In the same manner, this parameter also depends on the protein (BSA) effective charge [23] which undoubtedly affects significantly the process of BSA adsorption on charged electrode surface [8].…”

“…Recently [8,9] we have demonstrated that the mercury monolayer carbon fiber electrode doped with the atoms of metallic copper (Cu-MMCFE) is a powerful agent for recycling of biologically important redox systems accompanied by hydrogen (proton) transfer (reaction (3)) due to generation of highly chemically active hydrogen intermediates -H 0 (atomary hydrogen, a strong reductant) and H þ 2 (the molecular ion, a strong oxidant) under conditions where fast voltammetry (v (potential scan rate) > 100 V s À1 ) is utilized.…”

Novel ultrasensitive and ultrafast voltammetric determination of biological aminochromes on the copper nanodoped mercury monolayer carbon fiber electrode

“…Recently [6][7][8], we have demonstrated that the mercury monolayer carbon fiber electrode (MMCFE) is a powerful source of highly chemically active hydrogen intermediates -H 0 (atomary hydrogen, a strong reductant) and H þ 2 (the molecular ion, a strong oxidant) in conditions when the fast voltammetry (v (potential scan rate) > 100 V s À1 ) is utilised. Combining this electrode (by means of nanodoping of MMCFE by the metallic copper) with the Cu 2+/0 -system which is catalytically sensitive to the indicated hydrogen intermediates allows quantification of substances (species) consuming or supplying these intermediates.…”