Ultrasensitive and selective non-enzymatic glucose detection based on pt electrode modified by carbon nanotubes@ graphene oxide/ nickel hydroxide-Nafion hybrid composite in alkaline media

Abstract

A new enzymeless glucose sensor has been fabricated and its electrocatalytic oxidation has been investigated in alkaline medium directly on the Pt Electrode modified by Activated carbon nanotubes @ graphene oxide/ nickel hydroxide-Nafion hybrid composite (Pt\ACNT@GO\NHNPs\Nf). Under the optimized condition, the calibration curve is linear in the concentration range of 5-1100 µM using cyclic voltammetric method. The detection limit and sensitivity are 0.75 µM and 40 nA, respectively. The glucose sensor can be renewed easily in a reproducible manner by a simple polishing step and it has a long operational lifetime and short response time t90% < 1 s. In addition, the fabrication of Pt with nafion and nickel hydroxide powder was employed to eliminate the interference of ascorbic acid during the catalytic oxidation of glucose. The biosensor was used for determination of glucose in human blood serum and the oxidant with satisfactory results.

Simultaneous determination of levodopa and tryptophan using a modified glassy carbon electrode

“…Moreover, due to the electroactive properties of levodopa and tryptophan, those can be determined by electrochemical methods. Electrochemical technique is a good alternative to the aforementioned methods due to the faster response, higher selectivity, higher sensitivity, reproducibility, easy operation and lower cost [10][11][12][13][14].…”

Investigation of Adsorption of the Nitrosamine Molecule as a Carcinogen Agent on the AlN Nanotubes: A DFT Study

“…Nanocarbons, such as graphenes, graphynes, carbon nanotubes, and fullerene, have been widely studied [1,2]. Carbon nanotubes due to their unique physical, chemical, electronic, thermal, optical and mechanical properties, have many applications in nanotechnology and other fields of materials science [3][4][5][6][7][8]. The metallic and semiconducting behavior of CNTs depends on the diameter and chirality of the nanotubes, which makes their synthesis difficult for specific purposes [9].…”

Cu(I) Coordination Complex Precursor for Randomized CuOx Microarray Loaded on Carbon Nanofiber with Excellent Electrocatalytic Performance for Electrochemical Glucose Detection

“…The rapid determination of glucose concentration has attracted increasing interest in various fields, e.g., clinical diagnosis, food industry, wastewater treatment, and sustainable fuel cells [1,2]. Electrochemical techniques exhibit great potential for the development of next-generation glucose detection sensors due to their advantages, e.g., high sensitivity and selectivity, accuracy, simple instrumentation, low cost, and excellent compatibility with miniaturization.…”

“…A preconcentration step that involved 10 minutes accumulation at open circuit potential before SWV running led to the lowest limit of detection and the highest sensitivity for glucose detection (5419.77 µA·mM −1 ·cm −2 at + 1.1 V vs. Ag/AgCl) vs. Cu-based electrodes reported to date in literature.to modify the electrode as a non-enzymatic sensor for glucose detection taking its low cost, suitable redox properties, and excellent stability into account [7]. A large variety of copper/copper oxides modified electrodes having various shapes and sizes of copper nanoparticles have been reported to date for the non-enzymatic detection of glucose [1,2,[7][8][9][10][11][12][13][14][15][16][17][18][19]. Moreover, the role of the carbon substrate in enhancing the electrochemical performance of the copper-based nanostructured carbon electrode has been investigated [20][21][22].…”