Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics

Abstract

The identification of ancient wool is of great significance in archaeology; however, conventional methods are unwieldy or even ineffective when testing contaminated or severely degraded ancient samples. Therefore, it is...

Present Status and Perspectives of Graphene and Graphene‐related Materials in Cultural Heritage

“…[ 215 ] Indeed, GRMs can stably immobilize a high number of antibodies suitable for the specific interaction with the target analyte on the artifact, an approach already successfully tested in cultural heritage for the determination of keratin in ancient wools. [ 216 ] A wider detection range and a much lower detection limit of keratin compared to traditional indirect enzyme‐linked immunosorbent assay (ELISA) was achieved, paving the way for a new strategy to investigate the origin and diffusion of ancient textiles. Considering the versatility of antibodies and the great richness of options offered by the chemical versatility of GRMs, ultrasensitive electrochemical immunosensors can identify residual traces of the original binders or coatings that are hardly detectable with traditional spectroscopy techniques (e.g., FTIR, Raman).…”

In situ detection of silk fibroin using a dual recognition strategy with a flexible pressure immunosensor

“…1 In the Middle Ages, silk became a world-famous luxury good and the "golden card" of Chinese culture through the Silk Road. [2][3][4] Along this road, cultural exchanges and collisions between the East and the West have promoted cultural and technological development. 5 Therefore, it is of great historical and cultural value to explore the ageing and preservation of silk relics, especially the origin of silk.…”