Ultrasensitive PCR-Free detection of whole virus genome by electrochemiluminescence

Nikolaou, Pavlos; Sciuto, Emanuele Luigi; Zanut, Alessandra; Petralia, Salvatore; Valenti, G.; Paolucci, Francesco; Prodi, Luca; Conoci, Sabrina

doi:10.1016/j.bios.2022.114165

Cited by 19 publications

(15 citation statements)

References 64 publications

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“…Recently, numerous ECL-POCT devices have been developed to detect viruses. 52,53,[79][80][81] For antigen detection, Egashira et al 53 reported an ECL based immunosensor for the detection of H1N1 (Fig. 4A), in which an Au electrode modified with a hemagglutinin (HA) peptide was used as the working electrode.…”

Section: Public Health Surveillancementioning

confidence: 99%

Electrochemiluminescence devices for point-of-care testing

Ying

Zhou

et al. 2023

Sens. Diagn.

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Section: Public Health Surveillancementioning

confidence: 99%

Electrochemiluminescence devices for point-of-care testing

Ying

Zhou

et al. 2023

Sens. Diagn.

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“…Moreover, Pavlos and colleagues [ 81 ] recently suggested a new molecular biosensor for detecting Hepatitis B whole genome. The DNA sensor is based on a surface cooperative hybridization at a miniaturized gold electrode in conjunction with an ECL detection approach utilizing the [Ru (phen) 2 dppz] 2+ complex.…”

Section: Ecl Biosensors For Viruses Detectionmentioning

confidence: 99%

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Sobhanie¹,

Salehnia²,

Xu³

et al. 2022

TrAC Trends in Analytical Chemistry

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“…To the best of our knowledge, the MPXV entry receptor is still unknown; the discovery of the MPXV entry receptor and the development of MPXV sensors based on the entry receptor could be useful future developments. Novel MPXV biosensors could be developed based on photonics [ 95 ], quantum dots [ 96 ], electrochemiluminescence [ 97 ], electrochemical transduction, lab on a chip [ 30 ], CRISPR technology [ 98 , 99 ], and other approaches [ 100 , 101 , 102 , 103 ]. Introducing smart diagnostic systems based on WWE is anticipated to be a good future work to detect asymptomatic cases.…”

Section: Conclusion and Prospectsmentioning

confidence: 99%

Current and Perspective Sensing Methods for Monkeypox Virus

et al. 2022

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The outbreak of the monkeypox virus (MPXV) in non-endemic countries is an emerging global health threat and may have an economic impact if proactive actions are not taken. As shown by the COVID-19 pandemic, rapid, accurate, and cost-effective virus detection techniques play a pivotal role in disease diagnosis and control. Considering the sudden multicountry MPXV outbreak, a critical evaluation of the MPXV detection approaches would be a timely addition to the endeavors in progress for MPXV control and prevention. Herein, we evaluate the current MPXV detection methods, discuss their pros and cons, and provide recommended solutions to the problems. We review the traditional and emerging nucleic acid detection approaches, immunodiagnostics, whole-particle detection, and imaging-based MPXV detection techniques. The insights provided in this article will help researchers to develop novel techniques for the diagnosis of MPXV.

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Ultrasensitive PCR-Free detection of whole virus genome by electrochemiluminescence

Cited by 19 publications

References 64 publications

Electrochemiluminescence devices for point-of-care testing

Electrochemiluminescence devices for point-of-care testing

Recent trends and advancements in electrochemiluminescence biosensors for human virus detection

Current and Perspective Sensing Methods for Monkeypox Virus

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