Ultrasonic and computational study of intermolecular association through hydrogen bonding in aqueous solutions of d-mannitol

Ultrasonic, DFT and FT-IR studies on hydrogen bonding interactions in aqueous solutions of diethylene glycol

“…This confirms the presence of strong solute-256 solvent interactions through dipole-dipole interactions of the \OH 257 groups and an oxy group of DEG with the surrounding water molecules 258[8,9].…”

“…As observed in Table 2, the ultrasonic velocity for the DEG solutions In aqueous DEG solutions, it is observed ( Fig. 3 and Table 2) that the through intermolecular hydrogen bonding [8,9]. (Table 2).…”

“…The more stable 219 and dominant conformation of DEG in water is Q6 the preferential way 220 for the greater association of molecules in aqueous DEG solutions. The 221 ultrasonic and DFT studies on intermolecular association through hy-222 drogen bonding in aqueous solutions of D-mannitol and glycerol[8,9] 223 have also confirmed the formation of hydrogen bonds between hydro-224 philic hydroxyl groups and water in a particular hydrated pattern of sol-225 ute molecules. In aqueous solutions of DEG, it is observed that Q7 there is a 226 steady increase of ultrasonic velocity with the increase of DEG concen-227 tration.…”

“…33 © 2014 Published by Elsevier B.V. The alcoholic cryoprotective additives (CPAs) -diol, triol and polyol 40 play an important role in effective cryopreservation [1][2][3][4][5][6][7][8][9][10]. Cryopreser-41 vation is an effective method for the long-term storage of living cells or 42 tissues at freezing temperature.…”

“…In a two point potency scale, ethylene glycol 57 (EG) is an ineffective CPA for the storage of Sclerospora spores [17] 58 while Q5 it is an effective compound in preservation of human embryos 59 using a slow-freezing protocol [1]. The toxicity is also an important fac-60 tor in employing the CPA in many applications, including antifreeze, 61 cosmetics and pharmaceutical products [9,18]. In an effective long-62 term storage, amphiphilic alcoholic compounds like EG, propylene gly-63 col (PG), and glycerol, have been widely employed to protect bio cells 64 against freezing damage and stabilization of proteins [19].…”