Ultrasonic Tissue Characterization of Renal Cell Carcinoma Tissue

Sasaki, Hiraku; Tanaka, Motonao; Saijo, Yoshihumi; Okawai, Hiroaki; Terasawa, Yasuo; Nitta, Shin Ichi; Suzuki, Kiichi

doi:10.1159/000189291

Cited by 25 publications

(7 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Acoustic microscopy for medicine and biology has been developed for more than twenty years at Tohoku University [1][2][3][4][5][6]. The application of acoustic microscopy in medicine and biology has three major features and objectives.…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic intensity microscopy for imaging of living cells

et al. 2009

Self Cite

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Ultrasonic intensity microscopy for imaging of living cells

et al. 2009

Self Cite

View full text Add to dashboard Cite

“…Multimodal ultrasound microscope is a kind of acoustic microscopy which is used as a conventional scanning acoustic microscope, ultrasound impedance microscope or three-dimensional ultrasound microscope. The objectives of our research project [1][2][3][4][5][6][7][8][9] are to measure the sound speed of biological tissues, to assess the relation between sound speed and intensities of clinical ultrasound images and to evaluate the tissue degeneration from the biomechanical point of view.…”

Section: Background / Objectivesmentioning

confidence: 99%

Multimodal ultrasound microscopy for biomedical imaging

Saijo

2013

The Journal of the Acoustical Society of America

Self Cite

View full text Add to dashboard Cite

Acoustic microscopy provides not only high resolution imaging but also basic data for interpreting clinical ultrasound images and information on biomechanics of the tissues. Multimodal ultrasound microscope is developed for quantitative measurement of sound speed of the tissue. The frequency dependent characteristics of the amplitude and phase of a single pulse deduce the tissue thickness and sound speed. Specific acoustic impedance and elastic bulk modulus are derived by the sound speed and density of the tissue. Ultrasound impedance microscope visualizes microscopic image of the tissue surface by just touching the probe to the tissue. The reflection from the interface between the tissue and plastic plate is obtained to visualize two-dimensional distribution of specific acoustic impedance of the tissue. The multimodal ultrasound microscope realized conventional C-mode, surface impedance mode, B-mode, 3D mode and combination of photoacoustic imaging. The series of the ultrasound measurements of gastric cancer, renal cancer, prostatic cancer, myocardial infarction, atherosclerosis, cartilage-bone complex and brain have provided important information for clinical ultrasound imaging and pathophysiology from the point of view of biomechanics. Development of higher frequency transducer or arrayed transducer with newest technologies would realize higher resolution imaging and easier handling.

show abstract

“…The other clinical data obtained by the present method have been shown previously in the literature. [13][14][15] Thickness Other Than 10 µm For tissue specimens other than 10 µm in thickness, Figure 12 shows examples of 6-and 11-µm thickness. Figure 12, A and B, shows experimen-tal results of attenuation (decrease in magnitude) and phase shift.…”

Section: Stomach Tissuesmentioning

confidence: 99%