Ultrasonographic evaluation of endometrial changes using computer assisted image analysis

Chou, Szu Yuan; Chen, Chih-Yen; Chow, Pui Ki; Hsu, Chien Chin; Hsu, Meng‐Ting; Chiang, Huihua Kenny

doi:10.1111/j.1447-0756.2010.01218.x

Cited by 10 publications

(6 citation statements)

References 11 publications

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“…However, it has been used in other areas of medicine requiring histogram-based analysis of medical imaging. 40 – 44 At the time of this manuscript was being prepared, there were 789 studies that came up under the search term “ImageJ” on PubMed. Finally, the use of two different functional questionnaires may have skewed interpretation of the functional data, due to lack of a consistent method of functional data reporting.…”

Section: Discussionmentioning

confidence: 99%

Anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow nucleated cells: a case series

Centeno¹,

Pitts²,

Al‐Sayegh³

et al. 2015

JPR

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IntroductionThis was a prospective case series designed to investigate treatment for anterior cruciate ligament (ACL) tears using an injection of autologous bone marrow concentrate.MethodsConsecutive adult patients presenting to a private outpatient interventional musculoskeletal and pain practice with knee pain, ACL laxity on exam, and magnetic resonance imaging (MRI) evidence of a grade 1, 2, or 3 ACL tears with less than 1 cm retraction were eligible for this study. Eligible patients were treated with an intraligamentous injection of autologous bone marrow concentrate, using fluoroscopic guidance. Pre- and postprocedural sagittal MRI images of the ACLs were analyzed using ImageJ software to objectively quantify changes between pre- and posttreatment scans. Five different types of measurement of ACL pixel intensity were examined as a proxy for ligament integrity. In addition pain visual analog scale (VAS) and Lower Extremity Functional Scale (LEFS) values were recorded at baseline and at 1 month, 3 months, 6 months, and annually postinjection. Objective outcomes measured were pre- to post-MRI measurement changes, as analyzed by the ImageJ software. Subjective outcomes measured were changes in the VAS and LEFS, and a self-rated percentage improvement.ResultsSeven of ten patients showed improvement in at least four of five objective measures of ACL integrity in their postprocedure MRIs. In the entire study group, the mean gray value, median, raw integrated density, and modal gray value all decreased toward low-signal ACLs (P=0.01, P=0.02, P=0.002, and P=0.08), indications of improved ligament integrity. Seven of ten patients responded to the self-rated metrics follow up. The mean VAS change was a decrease of 1.7 (P=0.25), the mean LEFS change was an increase of 23.3 (P=0.03), and mean reported improvement was 86.7%.ConclusionBased on this small case series, autologous bone marrow concentrate shows promise in the treatment of grade 1, 2, and possibly grade 3 ACL tears without retraction. Further investigation using a controlled study design is warranted.

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Section: Discussionmentioning

confidence: 99%

Anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow nucleated cells: a case series

Centeno¹,

Pitts²,

Al‐Sayegh³

et al. 2015

JPR

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“…In this study, a new optical quantification technique based on ImageJ analysis software has been developed. The efficacy of this software for image processing and analysis has been demonstrated in many publications describing the analysis of ultrasonographic images , the quantification of fluorescence signals , adipose tissue , and leukocyte adhesion .…”

Section: Discussionmentioning

confidence: 99%

Er:YAG Laser Activation of Sodium Hypochlorite for Root Canal Soft Tissue Dissolution

et al. 2013

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“…Two quantitative terms were computed from the fluorescence images using Image J software package. 42 The first term was the mean pixel value of the fluorescence images in the entire sample area. The second term was the mean pixel values of fluorescence images only inside thr tumor and at the boundary of the tumor for each sample.…”

Section: Fluorescence Scannermentioning

confidence: 99%

Photoacoustic imaging enhanced by indocyanine green-conjugated single-wall carbon nanotubes

Zanganeh¹,

Li²,

Kumavor³

et al. 2013

J. Biomed. Opt

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A photoacoustic contrast agent that is based on bis-carboxylic acid derivative of indocyanine green (ICG) covalently conjugated to single-wall carbon nanotubes (ICG/SWCNT) is presented. Covalently attaching ICG to the functionalized SWCNT provides a more robust system that delivers much more ICG to the tumor site. The detection sensitivity of the new contrast agent in a mouse tumor model is demonstrated in vivo by our custom-built photoacoustic imaging system. The summation of the photoacoustic tomography (PAT) beam envelope, referred to as the "PAT summation," is used to demonstrate the postinjection light absorption of tumor areas in ICG- and ICG/SWCNT-injected mice. It is shown that ICG is able to provide 33% enhancement at approximately 20 min peak response time with reference to the preinjection PAT level, while ICG/SWCNT provides 128% enhancement at 80 min and even higher enhancement of 196% at the end point of experiments (120 min on average). Additionally, the ICG/SWCNT enhancement was mainly observed at the tumor periphery, which was confirmed by fluorescence images of the tumor samples. This feature is highly valuable in guiding surgeons to assess tumor boundaries and dimensions in vivo and to achieve clean tumor margins to improve surgical resection of tumors.

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Ultrasonographic evaluation of endometrial changes using computer assisted image analysis

Abstract: Ultrasonographic images analyzed using computer assisted image analysis software and gray level histogram are useful in assessing the physiological state of the endometrium.

Cited by 10 publications

References 11 publications

Anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow nucleated cells: a case series

Anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow nucleated cells: a case series

Er:YAG Laser Activation of Sodium Hypochlorite for Root Canal Soft Tissue Dissolution

Photoacoustic imaging enhanced by indocyanine green-conjugated single-wall carbon nanotubes

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