Ultrasonography of simple intratesticular cysts: a 13 year experience in a single centre

Al-Jabri, Talal; Misra, Saumya; Maan, Zeshaan N.; Khan, Khalid; Coker, Charles; Thompson, Phil

doi:10.1186/1746-1596-6-24

Cited by 8 publications

(10 citation statements)

References 12 publications

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“…Up till now LBC slides have been digitized by scanning the slides with several layers to cover the whole cell distribution along the z-axis. For example in [31], 15–20 µm is noted as a suitable range for scanning LBC slides, in [15] the slides are scanned at 31.5 µm, in [16] the authors used 20 µm and in [32] the authors conclude that the optimal number of focal planes remains unknown for cytology. Multi-layered imaging substantially hinders the subsequent manual or automatic image processing.…”

Section: Discussionmentioning

confidence: 99%

Semantic Focusing Allows Fully Automated Single-Layer Slide Scanning of Cervical Cytology Slides

et al. 2013

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Liquid-based cytology (LBC) in conjunction with Whole-Slide Imaging (WSI) enables the objective and sensitive and quantitative evaluation of biomarkers in cytology. However, the complex three-dimensional distribution of cells on LBC slides requires manual focusing, long scanning-times, and multi-layer scanning. Here, we present a solution that overcomes these limitations in two steps: first, we make sure that focus points are only set on cells. Secondly, we check the total slide focus quality. From a first analysis we detected that superficial dust can be separated from the cell layer (thin layer of cells on the glass slide) itself. Then we analyzed 2,295 individual focus points from 51 LBC slides stained for p16 and Ki67. Using the number of edges in a focus point image, specific color values and size-inclusion filters, focus points detecting cells could be distinguished from focus points on artifacts (accuracy 98.6%). Sharpness as total focus quality of a virtual LBC slide is computed from 5 sharpness features. We trained a multi-parameter SVM classifier on 1,600 images. On an independent validation set of 3,232 cell images we achieved an accuracy of 94.8% for classifying images as focused. Our results show that single-layer scanning of LBC slides is possible and how it can be achieved. We assembled focus point analysis and sharpness classification into a fully automatic, iterative workflow, free of user intervention, which performs repetitive slide scanning as necessary. On 400 LBC slides we achieved a scanning-time of 13.9±10.1 min with 29.1±15.5 focus points. In summary, the integration of semantic focus information into whole-slide imaging allows automatic high-quality imaging of LBC slides and subsequent biomarker analysis.

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Section: Discussionmentioning

confidence: 99%

Semantic Focusing Allows Fully Automated Single-Layer Slide Scanning of Cervical Cytology Slides

et al. 2013

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“…Кисты паренхимы яичка могут наблюдаться в любом возрасте, но наиболее часто встречаются у мужчин старше 40 лет [9,10]. Средний возраст пациентов с простыми кистами яичка, по данным наиболее крупных из опубликованных исследований, составил от 59 до 64,5 года [4,8,11].…”

Section: эпидемиологияunclassified

Simple intratesticular cysts: literature review

Shormanov

Ryzhkov

Sokolova³

2023

PoMPh

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Introduction. Until recently, simple cysts of the testicular parenchyma were considered extremely rare pathology. Recently, this condition has been diagnosed more often, which is largely due to the widespread use of ultrasound examination of the scrotum. To date, a unified approach to the management of patients with this nosology has not been developed, which served as the basis for a review of the literature on simple cysts of the testicular parenchyma.Results. Simple cysts of the testicular parenchyma are observed in 8–10 % of patients. The etiology of simple intratesticular cysts remains unknown. Small cysts of the testicular parenchyma are most often asymptomatic, pain symptoms of a nature for large cysts larger than 2 cm. Asymptomatic single cysts of the testicular parenchyma do not require surgical treatment and probably need dynamic monitoring. In patients with symptomatic and multiple cysts, surgical treatment should be recommended. Preference should be given to organpreserving techniques in the form of cyst resection/enucleation. Orchiectomy for the treatment of simple intratesticular cysts should be considered in exceptional cases.

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“…9 The postulated aetiology of intra-testicular simple cysts includes idiopathic/congenital, post-traumatic, postinfective or postsurgical manifestations. 16 They are most often solitary and frequently located adjacent to the mediastinum testes.…”

Section: Benign Testicular Lesionsmentioning

confidence: 99%

“…A follow-up ultrasound scan over an unspecified period of time, is however advised for symptomatic intra-testicular simple cysts so as to ensure that no interval increase in size or alteration in imaging characteristics occurs. 16…”

Section: Benign Testicular Lesionsmentioning

confidence: 99%

“…Posterior acoustic enhancement is not usually a feature due to the keratin and squamous components of its capsule; as a result these lesions can be differentiated from simple cysts. 16, 21 Horstman et al . reported that most malignant tumours measuring 1.6 cm or larger in size reliably show a degree of internal vascularity and that an avascular lesion in lesions of this size or more is suggestive of a benign lesion (Figure 8).…”

Section: Benign Testicular Lesionsmentioning

confidence: 99%

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Testicular, Epididymal and Adnexal Ultrasound: A Pictorial Review. Part 1: Testicular Ultrasound

2013

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Diagnostic ultrasound is considered to be the gold standard imaging modality for testicular assessment. As a result, it is frequently encountered by general radiologists and sonographers on daily ultrasound lists as well as by radiology residents out of hours. The main strength of diagnostic ultrasound in testicular assessment is that the high-frequency linear transducers utilized reproduce high-resolution images allowing accurate assessment of the testicular parenchyma. The fact that no ionizing radiation is utilized is particularly important as many patients on whom a testicular scan is requested are young or middle aged and the testis as an organ is very radiosensitive. This pictorial review comprises a range of illustrated images of congenital, benign, malignant, infection, polyorchidism and prosthesis-related pathologies collated over a two-year period at our institution.

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Ultrasonography of simple intratesticular cysts: a 13 year experience in a single centre

Cited by 8 publications

References 12 publications

Semantic Focusing Allows Fully Automated Single-Layer Slide Scanning of Cervical Cytology Slides

Semantic Focusing Allows Fully Automated Single-Layer Slide Scanning of Cervical Cytology Slides

Simple intratesticular cysts: literature review

Testicular, Epididymal and Adnexal Ultrasound: A Pictorial Review. Part 1: Testicular Ultrasound

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