Ultrasound and Biochemical First Trimester Markers as Predictive Factors for Intrauterine Growth Restriction

Martin, A.; Perez, Marta; Galán, Sebastián Manzanares

doi:10.23937/2377-9004/1410109

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…Previous studies have reported on the use of βhCG in maternal serum aneuploidy screening [20,21] in combination with ultrasound nuchal translucency/crown rump length [22] or Dopplers [23,24] and have been correlated with placental abruption, intrauterine growth restriction (IUGR), low birth weight, preterm birth, SGA, and preeclampsia in natural conceptions. Previous findings have been inconsistent in that late firsttrimester βhCG values in natural conceptions may only be mildly reduced or not significantly altered, while in the second trimester, βhCG values may be elevated in pregnancies with preeclampsia and IUGR [24].…”

Section: Discussionmentioning

confidence: 99%

Association of Early Beta Human Chorionic Gonadotropin With Ischemic Placental Disease in Singleton Pregnancies After In Vitro Fertilization

Shah¹,

Modest²,

Hacker³

et al. 2022

Cureus

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Objectives: To evaluate whether an initial or two-day percent increase in serum beta-human chorionic gonadotropin (βhCG) is associated with ischemic placental disease (IPD) in singleton pregnancies after autologous or donor IVF.Study design: This was a secondary analysis of a retrospective cohort study of deliveries linked to IVF cycles at a single academic tertiary hospital and infertility treatment center. We included all patients (≥18 years old) who had a singleton live birth or intrauterine fetal demise (IUFD) resulting from either autologous fresh (n=1,347), autologous frozen (n=454), or donor (n=253) IVF cycles.Main outcome reassures: The primary outcome was a composite outcome of IPD or IUFD due to placental insufficiency. IPDs included preeclampsia, placental abruption, and small for gestational age (SGA).Results: Neither initial βhCG nor two-day percent increases in βhCG were associated with an increased risk of IPD for any type of IVF cycle. Initial and two-day percent increases in βhCG were significantly higher when comparing frozen with fresh IVF and donor with autologous IVF (all P≤0.01).Conclusions: Among singleton autologous and donor IVF cycles, the initial and two-day percent increase in serum βhCG were not associated with IPD or its components. However, significant βhCG differences existed by cycle type and oocyte source.

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Section: Discussionmentioning

confidence: 99%

Association of Early Beta Human Chorionic Gonadotropin With Ischemic Placental Disease in Singleton Pregnancies After In Vitro Fertilization

Shah¹,

Modest²,

Hacker³

et al. 2022

Cureus

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show abstract

“…Neonatal complications include haematological and metabolic problems and impaired thermoregulation. In addition, intraventricular haemorrhage, necrotizing enterocolitis, seizures, sepsis, respiratory distress syndrome, retinopathy of prematurity and neonatal death contribute to the perinatal morbidity [11].…”

Section: Discussionmentioning

confidence: 99%

Cerebroplacental Doppler Indices in Intrauterine Growth Restriction Fetuses before and after Maternal Dexamethasone Management

Belal

Borg

Elbadry

et al. 2022

JAMMR

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Background: IUGR increases the risk for intrapartum asphyxia, preterm delivery, and risks associated with preterm delivery, including but not limited to respiratory distress syndrome, intraventricular hemorrhage, and necrotizing enterocolitis. Doppler ultrasound gives us information on the vascular resistance and, indirectly, on the blood flow. The aim of this work is to assess any change in the cerebroplacental Doppler ratio before and after receiving Dexamethasone on pregnancies complicated by fetal growth restriction. Methods: A prospective study was conducted at the Department of Obstetrics and Gynecology, Faculty of Medicine, Tanta University on 60 pregnant females after counseling and explaining of the procedure to patients, assurance of confidentiality, anonymity and their acceptance. Results: The mean GA was 32 weeks and mean weigh of the fetus was 1165 kg with mean amniotic fluid index 5.85 cm. There was significant increase in MCA PI after treatment p-value <0.001. there was significant decrease in UMA PI after treatment with p-value <0.001. Conclusions: Dexamethasone use in cases of IUGR is associated with significant improvement in the form of decrease in umbilical artery S/D ratio and pulsatility index.

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Maternal energy metabolism and angiogenesis genes polymorphisms in fetal growth restriction

et al. 2021

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Ultrasound and Biochemical First Trimester Markers as Predictive Factors for Intrauterine Growth Restriction

Cited by 3 publications

References 17 publications

Association of Early Beta Human Chorionic Gonadotropin With Ischemic Placental Disease in Singleton Pregnancies After In Vitro Fertilization

Association of Early Beta Human Chorionic Gonadotropin With Ischemic Placental Disease in Singleton Pregnancies After In Vitro Fertilization

Cerebroplacental Doppler Indices in Intrauterine Growth Restriction Fetuses before and after Maternal Dexamethasone Management

Maternal energy metabolism and angiogenesis genes polymorphisms in fetal growth restriction

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