Ultrasound-assisted extraction of bioactive compounds from green tea leaves and clarification with natural coagulants (chitosan and Moringa oleífera seeds)

Bindes, Marlon Menezes Maciel; Reis, Miria Hespanhol Miranda; Cardoso, Vicelma Luiz; Boffito, Daria C.

doi:10.1016/j.ultsonch.2018.10.014

Cited by 71 publications

(17 citation statements)

References 43 publications

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“…The leaves contain a large amount of chlorophyll, and when they are thick and fleshy, they present large quantities of waxes and resins. In recent years, some researchers have worked in the extraction of flavonoids from some leaves, for example, from green tea ( Camellia sinensis ) [ 21 ], mandarin ( Citrus deliciosa Tenore) [ 22 ], and Cecropia species [ 23 ].…”

Section: Natural Sources Of Flavonoidsmentioning

confidence: 99%

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Luna

Ramírez-Garza

Saldivar

2020

The Scientific World Journal

170

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The flavonoids are compounds synthesized by plants, and they have properties such as antioxidant, anticancer, anti-inflammatory, and antibacterial, among others. One of the most important bioactive properties of flavonoids is their antioxidant effect. Synthetic antioxidants have side toxic effects whilst natural antioxidants, such as flavonoids from natural sources, have relatively low toxicity. Therefore, it is important to incorporate flavonoids derived from natural sources in several products such as foods, cosmetics, and drugs. For this reason, there is currently a need to extract flavonoids from plant resources. In this review are described the most important parameters involved in the extraction of flavonoids by unconventional methods such as ultrasound, pressurized liquid extraction, mechanochemical, high hydrostatic pressure, supercritical fluid, negative pressure cavitation, intensification of vaporization by decompression to the vacuum, microwave, infrared, pulsed electric field, high-voltage electrical discharges, and enzyme-assisted extraction. There are no unified operation conditions to achieve high yields and purity. Notwithstanding, progress has been achieved in the development of more advanced and environmentally friendly methods of extraction. Although in literature are found important advances, a complete understanding of the extraction process in each of the unconventional techniques is needed to determine the thermodynamic and kinetic mechanisms that govern each of the techniques.

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Section: Natural Sources Of Flavonoidsmentioning

confidence: 99%

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Luna

Ramírez-Garza

Saldivar

2020

The Scientific World Journal

170

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“…This technique has many advantages, since it decreases extraction and processing times, reduces energy and solvent consumption, and improves extraction performance. In addition, it is an easy, flexible, versatile and low-cost technique [15,16], as it has already been proven with other fruits such as grapes [17] or myrtle berries [18].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound-Assisted Extraction of Two Types of Antioxidant Compounds (TPC and TA) from Black Chokeberry (Aronia melanocarpa L.): Optimization of the Individual and Simultaneous Extraction Methods

et al. 2019

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Chokeberry (Aronia melanocarpa L.) contains a large number of bioactive compounds, which make of it a highly nutritional and antioxidant food with anti-cancer and anti-inflammatory properties. It has been recently seen its consumption increased because of its interesting composition and properties as a functional food. The ultrasound-assisted extraction method has been optimized, since it is a simple and fast technique to extract phenolic compounds, as well as anthocyanins, not only separately but also simultaneously. Multiple response has been optimized and demonstrated an effectiveness level similar to the individual ones. This represents a considerable reduction in costs, time and work. The optimal conditions for simultaneous extractions were: 54% methanol as extraction solvent at pH 2.72 and 69.4 °C temperature, 70% amplitude, 0.7 s cycle, and 0.5:18.2 g:mL sample mass/solvent volume ratio. The developed methods showed a high precision level with coefficients of variation lower than 5%. The methods were successfully applied to commercial samples. Additionally, the extraction of other compounds of biological interest, such as organic acids and sugars, was also studied.

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“…The experimental design method and the response surface methodology are closely related and the use of the response surface methodology is based on experimental data (Mäkelä 2017). This statistical model is an effective tool for optimizing complex processes and save time during the experimental phase (Menezes Maciel Bindes et al 2019). In the present study the effect of yeast extract and sampling time investigated on cell growth, azadirachtin, mevalonic acid and squalene accumulation and production and predicted their effects on accumulation and production by response surface methodology.…”

Section: ) Xanthonementioning

confidence: 99%

Improvement and Prediction of Secondary Metabolites Biosynthesis Under Yeast Extract Elicitation of Neem Cell Suspension Culture Using Response Surface Methodology

Farjaminezhad

Garoosi

2021

Preprint

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Neem is the medicinal plant used as antimalarial, antibacterial, antiviral, insecticide and antimicrobial. The aim of this study was investigate effect of yeast extract and sampling time on cell growth, secondary metabolites synthesis, SQS1 and MOF1 genes expression and prediction of secondary metabolites synthesis by response surface methodology. Highest fresh and dry cell weight were 580.25 g/L and 21.01 g/L obtained 6 days after addition 100 mg/L yeast extract. Highest azadirachtin accumulation and production were 16.08 mg/g DW and 219.78 mg/L obtained at 25 mg/L yeast extract for 2 and 4 days. Maximum mevalonic acid accumulation and production were 1.746 mg/g DW and 23.77 mg/L observed 2 days after addition 50 mg/L yeast extract addition. Highest amount of squalene accumulation (0.215 mg/g DW) and production (4.526 mg/L) were achieved 4 days after application of 50 mg/L yeast extract. Prediction results showed that highest azadirachtin accumulation (13.607 mg/g DW) and production (190.50 mg/L), mevalonic acid accumulation (0.500 mg/g DW) and production (5.57 mg/L) and squalene accumulation (0.301 mg/g DW) obtained by using 245 mg/L yeast extract for 2 days, 71 mg/L yeast extract for 2 days, 200 mg/L yeast extract for 4.96 days, whitout yeast extract for 6.54 days and 4 days, respectively and predicted that highest squalene production is achieved by long-term exposure to high concentrations of yeast extract. qRT-PCR analysis showed the maximum relative gene expression of SQS1 and MOF1 by addition 150 mg/L yeast extract for 4 days and 25 mg/L yeast extract for 2 days, respectively.

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Ultrasound-assisted extraction of bioactive compounds from green tea leaves and clarification with natural coagulants (chitosan and Moringa oleífera seeds)

Cited by 71 publications

References 43 publications

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Environmentally Friendly Methods for Flavonoid Extraction from Plant Material: Impact of Their Operating Conditions on Yield and Antioxidant Properties

Ultrasound-Assisted Extraction of Two Types of Antioxidant Compounds (TPC and TA) from Black Chokeberry (Aronia melanocarpa L.): Optimization of the Individual and Simultaneous Extraction Methods

Improvement and Prediction of Secondary Metabolites Biosynthesis Under Yeast Extract Elicitation of Neem Cell Suspension Culture Using Response Surface Methodology

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