Ultrasound Detection of Renal Anomalies Antenatally and Postnatal Outcome

Chandran, Jyoti Ramesh

doi:10.18410/jebmh/2014/268

Cited by 1 publication

(2 citation statements)

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“…There was a male predominance amongst the subjects screened for CAKUT in the study that was also reported in other studies by Nabeel S. Bondagji, 17 Hsain-Lan Chein, 25 Chandran 20 and Hindryckx. 26 The maternal risk factors like diabetes, obesity, alcohol consumption and exposure to teratogens were not observed in the study though a positive family history of renal diseases was obtained in five subjects suggestive of a genetic predisposition.…”

Section: Baseline and Clinical Characteristicssupporting

confidence: 86%

“…Blyth et al, Sairam et al, Chandran and Levi et al also reported that the incidence of hydronephrosis varied between 0.6-4.5% in non-selected population. 18,19,20,21 The severity of hydronephrosis was graded as per APD diameter. Mild variants with APD diameter <10 mm on antenatal scans of this anomaly were transient and resolved spontaneously on subsequent followup scans.…”

Section: Baseline and Clinical Characteristicsmentioning

confidence: 99%

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Congenital Renal and Urinary Tract Anomalies in Selected Neonates

Karambelkar¹,

Malwade²,

Agarkhedkar³

et al. 2016

jebmh

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BACKGROUND Congenital anomaly of kidney and urinary tract (CAKUT) are among the most common anomalies diagnosed prenatally. Early diagnosis and timely intervention can preserve renal function and avoid morbidity. AIMS AND OBJECTIVES To screen, select at-risk newborns for congenital renal and urinary tract anomalies by postnatal ultrasound and to study the pattern of distribution, clinical presentation and its correlation with antenatal scan. MATERIALS AND METHODS It was a prospective study. Postnatal ultrasound of 40 subjects fulfilling the inclusion criteria was performed on 4 th day of life. Postnatal ultrasound findings were compared with antenatal records and immediate postnatal clinical course was assessed. RESULTS Out of 40 high-risk selected screen patients, 14 subjects were identified to have CAKUT on postnatal USG on 4 th day of life. Hydronephrosis was the most common congenital renal anomaly with statistically good correlation with antenatal and postnatal scan (P <0.0001). Mild hydronephrosis detected on antenatal scan (with anterior pelvic diameter 7-9 mm) showed resolution on postnatal ultrasound in 3 subjects. The congenital anomalies in 4 cases were missed on antenatal USG. The number of LBW babies in the screened population was 60% and 64% babies with CAKUT were LBW. Family predisposition was seen in 12.5% of CAKUT population. CONCLUSION Congenital renal and urinary tract anomalies can be easily identified on antenatal and post natal ultrasound. LBW babies with family history of CAKUT or high-risk factors warrant radiological screening and biochemical evaluation. Hydronephrosis is the most common finding consistent in both the scans and had a good resolution rate. Prenatal screening would help in early identification of CAKUT anomalies and possible early surgical or medical intervention to prevent or slow ESRD.

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Section: Baseline and Clinical Characteristicssupporting

confidence: 86%