Ultrastructural analysis of the lamina cribrosa after radial optic neurotomy

Hasselbach, H.; Thale, Andreas B.; Bunse, A.; Paulsen, Friedrich; Roider, Johann

doi:10.1016/j.aanat.2009.02.010

Annals of Anatomy - Anatomischer Anzeiger

2009

DOI: 10.1016/j.aanat.2009.02.010

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Ultrastructural analysis of the lamina cribrosa after radial optic neurotomy

H. Hasselbach

Andreas B. Thale

A. Bunse

et al.

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Cited by 3 publications

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“…Others have proposed that the resolution of retinal vein occlusion and macular edema was linked to the formation of chorioretinal shunts at the location of the RON [10]. In an ultrastructural analysis of the lamina cribrosa after radial optic neurotomy other authors observed complete dissection of the scleral outlet in only 60 % of the cases and they hypothesized that the possible variable rate of incomplete dissections may be an explanation for the variations in edema resolution and visual recovery seen in different case series [11]. Another variable of importance for the outcome of surgery could be the vitrectomy itself.…”

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confidence: 99%

Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion

Konstantinidis

Bissig

Pournaras

et al. 2016

Klin Monatsbl Augenheilkd

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Our results compare very favorably with the natural history of CRVO. All patients demonstrated a trend to improved visual acuity, while only one of the patients developed neovascular complications. These results provide information on the potential long-term effect of PPV in patients with CRVO and may help to reassess the place of the surgical management of CRVO in patients who do not respond to medical treatment.

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confidence: 99%

Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion

Konstantinidis

Bissig

Pournaras

et al. 2016

Klin Monatsbl Augenheilkd

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Intravitreal dexamethasone implant for central retinal vein occlusion without macular edema

et al. 2019

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Background To evaluate the efficacy of an intravitreal dexamethasone (IVD) implant (Ozurdex®) for the treatment of central retinal vein occlusion (CRVO) without macular edema (ME). Methods A retrospective cohort study was designed, and 20 eyes of 20 patients diagnosed with non-ischemic CRVO without ME were included. A total of 10 CRVO eyes were observed without treatment, and another 10 CRVO eyes received a single IVD injection at baseline. Mean changes in pathomorphologic parameters of fundus and optical coherence tomography parameters were measured at baseline and at 1, 3, 6, and 12 months. Results The decreases in venous tortuosity ( p = 0.014 for superior; 0.036 for inferior arcades) and width ( p = 0.024 for superior; 0.003 for inferior arcades) from baseline to 12 months after injection were significantly greater in the treated group than the observed group. The improvements in RNFL swelling ( p = 0.010) and retinal hemorrhage ( p = 0.006) were also significantly greater in the treated group. Visual symptom improvement was significantly faster in the treated group ( p = 0.001). In two cases, IVD injection resulted in complete resolution of cilioretinal artery occlusion associated with the CRVO, leading to complete visual recovery in 1 week. None of the treated eyes showed signs of ME development, ischemia progression, or neovascularization. Conclusions IVD implant was significantly effective in improving venous engorgement, retinal hemorrhage, RNFL swelling, and visual symptoms by presumed alleviation of disc swelling and venous outflow. This treatment may be a considerable treatment option in CRVO patients with no ME.

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Radial optic neurotomy in treating central retinal vein occlusion: a Meta-analysis

Chen

Shao

2016

Int J Ophthalmol

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Ultrastructural analysis of the lamina cribrosa after radial optic neurotomy

Cited by 3 publications

References 28 publications

Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion

Long-Term Functional and Anatomical Outcome of Radial Optic Neurotomy for Central Retinal Vein Occlusion

Intravitreal dexamethasone implant for central retinal vein occlusion without macular edema

Radial optic neurotomy in treating central retinal vein occlusion: a Meta-analysis

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