Ultrastructural studies of the effect of steroid hormones on pars recta secretions inBufo arenarum

Fernández, Silvia N.; Miceli, Dora C.; Whitacre, Cecilia M.

doi:10.1002/(sici)1097-4687(199701)231:1<1::aid-jmor1>3.0.co;2-k

Cited by 5 publications

(1 citation statement)

References 7 publications

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“…Furthermore, a protein named membrane cofactor protein identified in the inner membrane of human sperm cells with the ability of binding C 3 b has been thought to be involved in mammalian fertilization (Cervoni et al, 1992;Anderson et al, 1993). The fact that B. arenarum pars recta secretions contain trypsin-like proteases hormone-regulated during sexual cycle (Fernandez et al, 1984(Fernandez et al, , 1997, capable of activating the complement cascade, in analogy with hormone-regulation of complement activity in bovine (Fahmi and Hunter, 1985) and rabbit (Oliphant et al, 1984) follicular fluid, suggested further a potential association between these phenomenon in B. arenarum. Therefore, the goals of this study were, (i) to determine if C 3 -and CR3-like factors are present in eggs and/or sperm cells in B. arenarum; (ii) to assess the biological consequences of the inhibition of C 3 and CR3 analogs in B. arenarum fertilization.…”

Section: Introductionmentioning

confidence: 99%

Potential involvement of C3 complement factor in amphibian fertilization

Llanos

Whitacre

Miceli

2000

Comparative Biochemistry and Physiology - Part A: Molecular &Amp; Integrative Physiology

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Section: Introductionmentioning

confidence: 99%

Potential involvement of C3 complement factor in amphibian fertilization

Llanos

Whitacre

Miceli

2000

Comparative Biochemistry and Physiology - Part A: Molecular &Amp; Integrative Physiology

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Ultrastructural changes in the oviductal mucosa throughout the sexual cycle inBufo arenarum

et al. 1999

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Effect of steroid hormones on Bufo arenarum oviduct. Ultrastructural study

et al. 2007

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The endocrine regulation of the mucosa of the oviductal pars convoluta was analyzed by ultrastructural studies demonstrating that ovariectomy, together with a decrease in ovarian steroids circulating levels, caused a marked regression in this portion of Bufo arenarum oviduct. Twenty-five days after ovariectomy, a decrease in the depth of the epithelial and glandular layers was observed due to the notable loss of secretory cells, whose number was clearly smaller than in nonovariectomized females. The remaining secretory cells showed involution signs, with few secretory granules in their cytoplasm, little endoplasmic reticulum near poorly developed Golgi complexes and a large amount of lipid droplets. Cells in an advanced autolysis state were found in the lumen. These characteristics evidence a nonfunctional state of the pars convoluta. Treatment with 5alpha-dihydrotestosterone (DHT) completely reversed the ovariectomy effect, inducing pars convoluta growths and restoring the characteristics of epithelial and glandular secretory cells in the whole pars convoluta, with micrographs similar to the control. These same effects were observed after treatment with estradiol-17beta (E2), progesterone (P) o E(2)+P in the glandular layer of the whole pars convoluta, but only in the epithelial layer of the most anterior region of this duct. In the secretory cells of other segments these treatments induced the formation of granules of high electron density and homogeneous aspect. Each steroid had a particular effect on the pars convoluta. Although E2 and DHT induced the development of the organoids involved in the proteins biosynthesis, P and DHT acted as secretagogues.

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Ultrastructural studies of the effect of steroid hormones on pars recta secretions inBufo arenarum

Cited by 5 publications

References 7 publications

Potential involvement of C3 complement factor in amphibian fertilization

Potential involvement of C3 complement factor in amphibian fertilization

Ultrastructural changes in the oviductal mucosa throughout the sexual cycle inBufo arenarum

Effect of steroid hormones on Bufo arenarum oviduct. Ultrastructural study

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