Ultrastructure of ovarian preantral follicles and corpus luteum in Indian flying fox Pteropus giganteus (Brünnich)

The corpus luteum is an endocrine gland that synthesizes the steroid hormone progesterone. luteinizing hormone (LH) is a key luteotropic hormone that stimulates ovulation, luteal development, progesterone biosynthesis, and maintenance of the corpus luteum. Luteotropic and luteolytic factors precisely regulate luteal structure and function; yet, despite recent scientific progress within the past few years, the exact mechanisms remain largely unknown. In the present review, we summarize the recent progress towards understanding cellular changes induced by LH in steroidogenic luteal cells. Herein, we will focus on the effects of LH on inter-organelle communication and steroid biosynthesis, and how LH regulates key protein kinases (i.e., AMPK and MTOR) responsible for controlling steroidogenesis and autophagy in luteal cells.

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Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum

Przygrodzka

Plewes

Davis

2021

IJMS

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Ultrastructure of ovarian preantral follicles and corpus luteum in Indian flying fox Pteropus giganteus (Brünnich)

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References 21 publications

Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum

Luteinizing Hormone Regulation of Inter-Organelle Communication and Fate of the Corpus Luteum

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