Ultraviolet-induced crosslinking of solid poly(ethylene oxide)

Abstract

Poly(ethylene oxide) (PEO) of molecular weight from 200,000 to 2,000,000 was crosslinked by exposure to ultraviolet radiation with a high-pressure 150 W mercury lamp. Photochemical crosslinking of PEO proceeds in the presence of photoinitiators such as benzophenone and acetophenone which act as a hydrogen-abstracting agent. Gel fraction yield exceeds 90%, and the number-average molecular weight between crosslinks determined by equilibrium swelling in chloroform varies from 3,000 to 100,000. The degree of crosslinking can be controlled by changing the irradiation temperature.

X-ray Spectromicroscopy Study of Protein Adsorption to a Polystyrene−Polylactide Blend

“…The inclusion of PETA and other UV-initiated radical crosslinkers [32] to form PEObased biomaterials such as hydrogels [6,12] or micelles [13] for drug delivery is becoming increasingly common. In the formation of micelles, PETA is used to stabilize the hydrophobic core [26] and is likely not present at the air-substrate interface.…”

“…UV-initiated crosslinking of PEO with pentaerythritol triacrylate (PETA) or other radical crosslinkers [8] is becoming increasingly popular since PEO can be crosslinked in both solution and solid state [9,10]. The inclusion of PETA to form crosslinked PEO has been used in biomedical applications such as hydrogels [11,12] and micelles [13] for drug delivery, or to form chemically patterned surfaces for cell studies [14].…”

UV-Initiated Crosslinking of Poly(ethylene oxide) with Pentaerythritol Triacrylate in Solid State

“…[1,2] The pure polymer of PEO cannot be UV-crosslinked because of the absence of photosensitive chromophoric groups. On the other hand, powderlike PEO polymer can be heterogeneously crosslinked with multifunctional monomers like pentaerythritol triacrylate (PETA) using free-radical initiators.…”

An X‐ray Spectromicroscopy Study of Albumin Adsorption to Crosslinked Polyethylene Oxide Films

“…[8][9][10][11] Since PEO is soluble in water, techniques such as g, [12] UV [13,14] and electron irradiation [15] have been employed to crosslink the PEO chains to prevent mass loss upon protein exposure. UV-initiated crosslinking of PEO with pentaerythritol triacrylate (PETA) or other radical crosslinkers [16] is becoming increasingly popular, since PEO can be crosslinked in both solution and solid state. [17,18] The inclusion of PETA to form crosslinked PEO has been used in biomedical applications such as hydrogels [19] and micelles [20] for drug delivery, or to form chemically patterned surfaces for cell studies.…”

“…thritol triacrylate (PETA) or other radical crosslinkers [16] is becoming increasingly popular, since PEO can be crosslinked in both solution and solid state. [17,18] The inclusion of PETA to form crosslinked PEO has been used in biomedical applications such as hydrogels [19] and micelles [20] for drug delivery, or to form chemically patterned surfaces for cell studies.…”