Ultraviolet Radiation as Cataract Risk Factor � A Case Report

Dose-response function for lens forward light scattering after in vivo exposure to ultraviolet radiation

“…Müller-Breitenkamp et al [11] reported anterior and posterior subcapsular opacities in both eyes of a 65-year-old patient 30 years after unintended exposure to UVR. The patient received 0.7±2 kJ/m 2 per day UVR-B and -C during the winter season over 15 years.…”

“…The patient received 0.7±2 kJ/m 2 per day UVR-B and -C during the winter season over 15 years. The time interval of the exposure prior to the examination was confirmed by measuring the distance between the lens capsule and the cortical opacities [11].…”

UV DAMAGE TO THE EYE LENS: Further Results from Animal Model Studies: A review

“…We want to stress that this type of UV B radiation damage of the lens is characteristic only for the direct effect (damage in relatively close time connection to the irradiation by high dosages). In general we do not observe this type of opacity in human beings, only very occasional by accidents ( Figure 3) with unshielded (or defect safety constructions) UV sources in professional applications as mentioned already in the assessment of exposure [4][5][6]. Missing this type of cataract among the observed cataracts of epidemiological studies makes it difficult, to accept the frequently manifested opinion that UV radiation contributes to the higher frequency of cataracts in regions with elevated cosmic UV irradiation or in the population with higher UV radiation as professional hazard (bath attendants, fishermen, gardeners, farmers, sailors, roadmen, masons, workers in certain projects in chemical and pharmaceutical industry, lithography, copy machine operators, welders etc.)…”

UV-B-lnduced Cataract Model in Brown-Norway Rat Eyes Combined with Preadministration of Buthionine Sulfoximine

“…The movement of an terior cortical opacity area toward the nuclear region that was observed in the investigation had the same appearance as that seen in the UV-induccd cataract in a human case reported by Mueller-Breitenkamp et ai. [22], An unexpected result was that results of the combination treatment group with low UV-B irradiation (0.067 J/cm2) and gluta thione depression were not prominently dif ferent from those of the group receiving UV-B alone. The authors were able to induce rather prominent cortical cataracts without corneal damage in the group treated with UV-B alone.…”