Umbilical cord haemangioma associated with an eruptive cutaneous haemangioma in a female infant

Weyerts, Leah K.; Jones, Marilyn C.; Grafe, Marjorie R.; Scioscia, Angela L.

doi:10.1002/pd.1970130109

Cited by 10 publications

(7 citation statements)

References 5 publications

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“…The present case also showed an elevated MSAFP level at 16 weeks of gestation. In contrast, 2 cases with normal MSAFP levels in this condition have been reported as well [16,17]. Because of the rarity of this tumor, the diagnostic significance of MSAFP remains unclear.…”

Section: Discussionmentioning

confidence: 87%

“…They are attributed to the presence of coexisting factors, such as nonimmune hydrops fetalis [1,2], intrauterine growth retardation [3,4], fetal anomaly including other coexisting hemangiomas [5,12,17], severe fetal hemorrhage [3,6], and intrauterine fetal death [3,7,8] as well as maternal obstetrical complications [3]. Among these factors, causes of intrauterine fetal death have not been definitely established.…”

Section: Discussionmentioning

confidence: 99%

“…A total of 14 cases of prenatal ultrasonographic diagnosis of an umbilical cord hemangioma has been reported [1,2,4,5,[8][9][10][11][12][13][14][15][16][17]. With advancing technology and application of ultrasound and MSAFP evaluation in the second trimester, it may be possible to diagnose hemangiomas of the umbilical cord in early gestation.…”

Section: Discussionmentioning

confidence: 99%

“…The morbidity and mortality rate of umbilical cord hemangiomas have been reported to be F35% [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. They are attributed to the presence of coexisting factors, such as nonimmune hydrops fetalis [1,2], intrauterine growth retardation [3,4], fetal anomaly including other coexisting hemangiomas [5,12,17], severe fetal hemorrhage [3,6], and intrauterine fetal death [3,7,8] as well as maternal obstetrical complications [3].…”

Section: Discussionmentioning

confidence: 99%

“…Only a total of 30 cases with an F35% mortality rate due to this disorder have been reported [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. The high mortality rate is attributed to impaired umbilical circulation due to enlarged tumors, which resulted in nonimmune hydrops fetalis [1,2] and intrauterine growth retardation [3,4].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Hemangioma of the Umbilical Cord: Stenotic Change of the Umbilical Vessels

Kamitomo¹,

Sueyoshi

Matsukita

et al. 1999

Fetal Diagn Ther

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We report a rare case of an umbilical cord hemangioma diagnosed by ultrasound at 16 weeks of gestation. The umbilical cord consisted of a hemangioma nodule and pseudocysts near the placental insertion, a large gelatin-like swelling adjacent to the nodule on its fetal side, and a short normal part extending to the navel. At 17 weeks of gestation, this condition resulted in the intrauterine death of the fetus. Microscopically, there were communications between the capillary of the hemangioma and the umbilical vessels, verifying the origin of the tumor. Moreover, the umbilical vein and one of the arteries changed stenotically due to the intravascular proliferation of the hemangioma. These findings indicate the possibility of a pathological association between the umbilical cord hemangioma and fetal demise due to impaired umbilical circulation.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Hemangioma of the Umbilical Cord: Stenotic Change of the Umbilical Vessels

Kamitomo¹,

Sueyoshi

Matsukita

et al. 1999

Fetal Diagn Ther

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Multifocal rapidly involuting congenital hemangioma: A link to chorangioma

Mulliken

Bischoff

Kozakewich

2007

American J of Med Genetics Pt A

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Common infantile hemangioma is intriguing because of its variable presentation, rapid postnatal growth and slow regression in childhood. Interest in this tumor has increased with the recognition that it can be associated with structural anomalies in the craniofacial and ventral-caudal regions. The phenotype has expanded by characterization of rare vascular tumors that arise in the fetus and manifest at birth as rapidly involuting congenital hemangioma (RICH) or non-involuting congenital hemangioma (NICH). We describe a boy born with three RICH on the abdominal wall; one extended into the base of the umbilical cord. Two weeks later a small, infantile hemangioma arose on his neck. This patient stimulated a review of what is known about placental vascular tumors and their possible relationship to fetal and infantile hemangiomas. We suggest that chorangioma and umbilical cord hemangioma are clinically and histopathologically similar to cutaneous and hepatic RICH. These placental vascular tumors can also occur in conjunction with solitary and multiple infantile hemangiomas.

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Prenatal Diagnosis of Umbilical Cord Angiomyxoma

Grossi,

Astori,

Nakatani

et al. 2024

J of Ultrasound Medicine

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We describe two cases of umbilical cord (UC) angiomyxoma diagnosed prenatally by sonography in the second trimester of pregnancy. In both cases, a complex mass was detected at the placental insertion site, characterized by an echoic nodule surrounding the umbilical vessels and distal edematous Wharton's jelly. Follow‐up scans showed that the mass grew mainly at the expense of its edematous component, with normal uteroplacental Dopplers throughout the remaining of the pregnancy. However, late‐onset fetal growth restriction complicated the progress of pregnancy, requiring delivery by Cesarean section at 37 weeks' gestation in both cases. Neonatal courses were unremarkable. An extensive review of the English literature was also performed, collecting 45 similar cases including ours. Our experience as well as the review of the literature confirms that UC angiomyxoma is an uncommon, sporadic condition that is usually detected incidentally during prenatal sonography and presents as an isolated finding. Nevertheless, it represents a high‐risk condition for pregnancy complications including prematurity, fetal growth restriction, and fetal demise.

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Umbilical cord haemangioma associated with an eruptive cutaneous haemangioma in a female infant

Cited by 10 publications

References 5 publications

Hemangioma of the Umbilical Cord: Stenotic Change of the Umbilical Vessels

Hemangioma of the Umbilical Cord: Stenotic Change of the Umbilical Vessels

Multifocal rapidly involuting congenital hemangioma: A link to chorangioma

Prenatal Diagnosis of Umbilical Cord Angiomyxoma

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