Un corps étranger intracérébral de découverte fortuite conduit au diagnostic du syndrome de Munchausen par procuration

Abed, A.; Mustapha, R.; Chiha, M.

doi:10.1016/j.arcped.2011.08.005

Cited by 4 publications

(1 citation statement)

References 18 publications

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“…Multifactorial/polygenic HTG, previously known as familial hypertriglyceridemia, has no currently identified genetic locus. HTG typically manifests in adulthood; however, pediatric expression has increased due to childhood obesity ( 18 – 20 ). This condition results in Very Low-Density Lipoproteins (VLDL) overproduction and impaired catabolism of TG-rich lipoproteins resulting in HTG ( 14 , 21 ).…”

Section: Etiologies and Pathophysiology Of Hypertriglyceridemiamentioning

confidence: 99%

Hypertriglyceridemia-induced acute pancreatitis in children: A mini-review

2022

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Severe hypertriglyceridemia (HTG) is a known metabolic cause of acute pancreatitis (AP) in pediatric patients. The incidence of hypertriglyceridemia-induced acute pancreatitis (HTG-AP) is less well established in pediatric compared to adult patients. Studies in adults suggest that higher risk of AP occurs when triglyceride levels (TG) are >1,000 mg/dL. Most common etiologies for severe HTG in pediatric patients are either from primary hypertriglyceridemia, underlying genetic disorders of lipid and TG metabolism, or secondary hypertriglyceridemia, separate disease or exposure which affects TG metabolism. Most common theories for the pathophysiology of HTG-AP include hydrolysis of TG by pancreatic lipase to free fatty acids leading to endothelial and acinar cell damage and ischemia, as well as hyperviscosity related to increased chylomicrons. Though there are varying reports of HTG-AP severity compared to other causes of AP, a steadily growing body of evidence suggests that HTG-AP can be associated with more severe course and complications. Therapeutic interventions for HTG-AP typically involve inpatient management with dietary restriction, intravenous fluids, and insulin; select patients may require plasmapheresis. Long term interventions generally include dietary modification, weight management, control of secondary causes, and/or antihyperlipidemic medications. Though some therapeutic approaches and algorithms exist for adult patients, evidence-based management guidelines have not been well established for pediatric patients.

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Section: Etiologies and Pathophysiology Of Hypertriglyceridemiamentioning

confidence: 99%

Hypertriglyceridemia-induced acute pancreatitis in children: A mini-review

2022

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A late onset adult seizure due to intracerebral needle: case-based update

Bozkurt

Arac

2019

Childs Nerv Syst

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Background and aim Late-onset seizure due to intracerebral needle is a rare entity. Most of them were clinically asymptomatic and rarely presented with seizure. Sewing needles are used in homicidal attempt in infancy or early childhood before the closure of the fontanels. Because of sociologic, politic, and scientific deficiencies subject remained untouched. We tried shedding some light on this ambiguous phenomenon. Material and methods We report a 54-year-old man who was admitted to our neurosurgery outpatient department with epilepsy due to a sewing needle located in the left frontal lobe of the brain and made extensive literature review. Result Patient's physical and neurological examinations were completely normal. All biochemical and hematological tests were normal. Cranial tomography demonstrated a linear density at the left frontal lobe compatible with a sewing needle. Patient was followed-up with antiepileptic treatment with no seizure. Sixty cases from up-to-date literature and past cases were reviewed. Patients' ages differ from 4 days to 70 years. Our review showed four cases treated with antibiotics, 19 patients went to surgery, and others just followed-up with antiepileptic and other drugs. Conclusion Literature needs an autopsy series for a more intimate estimation. Due to psychosocial and legitimacy problems, matter should be handled cautiously and law enforcement agencies must be informed. Follow-up with medication is the first line of treatment with asymptomatic patients. Treatment is dictated by clinic onset, physical examination, and patient consent.

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Fabricated or induced illness in twins associated with insertion of trocar needles into their bodies

Houas

Fitouri

Hamzaoui

2018

Paediatrics and International Child Health

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Fabricated and/or induced illness (previously known as Munchausen syndrome by proxy) is a form of child abuse in which the perpetrator induces, exaggerates or fabricates illness in his/her child. Two-month-old twins were referred to the paediatric surgery centre with trocar needles lodged in different organs. A radiograph undertaken in one of them because of acute respiratory distress demonstrated needles in the heart and diaphragm which were removed surgically. The second twin, referred one week after his brother, had a needle deep in his liver and it was decided not to operate owing to the possibility of haemorrhage but, sadly, he died unexpectedly and the autopsy concluded that it was owing to sudden infant death syndrome. Because of a number of admissions to different units in the same hospital, there was a delay in the eventual diagnosis. Recurrent admissions to different hospital units should raise the suspicion of fabricated and/or induced illness.

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Un corps étranger intracérébral de découverte fortuite conduit au diagnostic du syndrome de Munchausen par procuration

Cited by 4 publications

References 18 publications

Hypertriglyceridemia-induced acute pancreatitis in children: A mini-review

Hypertriglyceridemia-induced acute pancreatitis in children: A mini-review

A late onset adult seizure due to intracerebral needle: case-based update

Fabricated or induced illness in twins associated with insertion of trocar needles into their bodies

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