Uncertainty Quantization of Fano Resonance Frequency Shift Measurement

Tran, Tuan Anh Pham; Santana, Elana Pereira de; Bolívar, P. Haring

doi:10.1109/irmmw-thz.2019.8874414

Cited by 1 publication

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to allow a transmission measurement of the biosensor, the measurement setup was extended with off-axis parabolic mirrors accomplishing a quasi-optical transmission path with an intermediate focus. Utilizing a specially adapted vacuum chuck, the sensor is placed in the focal plane 42 .This chuck combined with motorized linear stages (MICOS LS-65) enables a precise positioning during each measurement routine. In such a way, repeatable and comparable measurements of the individual query fields can be conducted before and after the functionalization with biomolecules.…”

Section: Thz Measurementsmentioning

confidence: 99%

High specificity THz metamaterial-based biosensor for label-free transcription factor detection in melanoma diagnostics

Richter,

Loth,

Wigger

et al. 2023

Sci Rep

View full text Add to dashboard Cite

In this work, we present a promising diagnostic tool for melanoma diagnosis. With the proposed terahertz biosensor, it was possible to selectively and sensitively detect the early growth response protein 2, a transcription factor with an increased activity in melanoma cells, from a complex sample of cellular proteins. Fundamentally, the sensor belongs to the frequency selective surface type metamaterials and consists of a two-dimensional array of asymmetrically, doubly split ring resonator unit cells. The single elements are slits in a metallic layer and are complemented by an undercut etch. This allows a selective functionalization of the active area of the sensor and increases the sensitivity towards the target analyte. Hereby, specific detection of a defined transcription factor is feasible.

show abstract

Section: Thz Measurementsmentioning

confidence: 99%