Uncommon case of histoplasmosis with oral manifestation: A case report of diagnosis in a South American patient

Dogenski, Letícia Copatti; Pasqualotto, Eduarda Mafaciolli; Dutra, Mateus José; Rovani, Gisele; Trentin, Micheline Sandini; Carli, João Paulo De

doi:10.1016/j.ijscr.2022.106920

Cited by 5 publications

(2 citation statements)

References 16 publications

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“…[4][5][6] However, only a few cases of localized histoplasmosis in the oral mucosa were reported. 4,5,[7][8][9] The present report demonstrates a rare case of primary localized oral histoplasmosis in a patient without immunologic deficiency. Thus, this disease must be included in the differential diagnosis of disseminated oral ulcers, especially in endemic regions, to prevent diagnostic pitfalls and treatment delays.…”

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confidence: 69%

Primary non‐disseminated histoplasmosis of the oral mucosa in an immunocompetent patient

et al. 2023

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confidence: 69%

Primary non‐disseminated histoplasmosis of the oral mucosa in an immunocompetent patient

et al. 2023

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“…Due to reduced immune function in AIDS patients, histoplasmosis typically presents as a disseminated infection in this population [31]. Patients with other immunosuppressive disorders, patients who are taking immunosuppressive drugs, infants, transplant recipients, and elderly patients are also likely to exhibit fullbody involvement [36][37][38].…”

Section: Histoplasmosismentioning

confidence: 99%

Acrophialophora: A Comprehensive Review of Clinical Guidelines and Diagnosis

Bhattaru¹,

Blanchard²,

Kunamneni³

et al. 2023

Cureus

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Acrophialophora is a saprotrophic genus of fungi found in both temperate and tropical regions. The genus is comprised of 16 species, with the subspecies A. fusispora and A. levis necessitating the most clinical concern. Acrophialophora is an opportunistic pathogen with a broad range of clinical manifestations; the fungus has been implicated in cases of fungal keratitis, lung infection, and brain abscess. Acrophialophora infection is particularly of concern for immunocompromised patients, who often present with a more severe disease course involving disseminated infection and may not exhibit typical symptoms. Early diagnosis and therapeutic intervention are critical to the successful clinical management of Acrophialophora infection. Guidelines for antifungal treatment have yet to be established, partially due to the lack of documented cases. Aggressive use of antifungal agents and long-term treatment is required, especially in immunocompromised patients and patients with systemic involvement, due to the potential for morbidity and mortality. In addition to outlining the rarity and epidemiology of the disease, this review provides an overview of the diagnosis and clinical management of Acrophialophora infection to facilitate an early diagnosis and appropriate interventions.

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Histoplasmosis Masquerading as Second Primary in Head and Neck Tumours - A Case Report

Gowthame

Annapurneswari

Kannan

et al. 2023

Indian J Otolaryngol Head Neck Surg

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Uncommon case of histoplasmosis with oral manifestation: A case report of diagnosis in a South American patient

Cited by 5 publications

References 16 publications

Primary non‐disseminated histoplasmosis of the oral mucosa in an immunocompetent patient

Primary non‐disseminated histoplasmosis of the oral mucosa in an immunocompetent patient

Acrophialophora: A Comprehensive Review of Clinical Guidelines and Diagnosis

Histoplasmosis Masquerading as Second Primary in Head and Neck Tumours - A Case Report

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