Uncommon site of metastasis from renal cell carcinoma: Case report

Ribeiro, Mauricio Alves; Ferreira, Caroline Petersen da Costa; Hernani, Bruno de Lucia; Szutan, Luiz Arnaldo; Mortati, Maria Carolina Galli; Pereira, Fabiana Toledo Bueno; Kater, Fabio

doi:10.1016/j.ijscr.2019.02.013

Cited by 6 publications

(5 citation statements)

References 12 publications

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“…RCC is considered as a tumor with a high metastatic potential: one third of the cases already have synchronous metastases at the time of diagnosis, and another 30% will develop metachronous disease, in some cases, more than a decade after the nephrectomy [7,8]. According to some authors, the most common distant sites for RCC metastases are the lunges, bones, liver, lymph nodes, adrenal gland and the brain [7,9,10]. In addition, pancreas, thyroid, skeletal muscle, skin, or soft tissue are potential rare sites for RCC metastases [3,11].…”

Section: Discussionmentioning

confidence: 99%

Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

Janevska

Shumkovski

Nikolova

et al. 2020

Prilozi

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Metastasis of renal cell carcinoma (RCC) to the pancreas is a rare entity accounting only 0.25–3% of all pancreatic tumors. We present a rare case of isolated three focal pancreatic metastases from RCC, occurring 15 years after the left nephrectomy. The majority of the pancreatic metastases are asymptomatic, as it was in case of our patient excluding the weight loss for the last three months. We demonstrate the importance of the medical history, radiological examinations, histological and immunohistochemical analysis in making a definitive diagnosis.

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Section: Discussionmentioning

confidence: 99%

Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

Janevska

Shumkovski

Nikolova

et al. 2020

Prilozi

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“…Moreover, as reported in one of our cases, digestive involvement of RCC metastasis includes gastrointestinal tract (stomach, duodenum, colon), ampulla of Vater and gallbladder in addition to the pancreas. Metastases can occur simultaneously in GI sites, as in our case, or at different timepoints during follow-up [ 20 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ].…”

Section: Discussionmentioning

confidence: 99%

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

et al. 2023

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Metastasis to the pancreas represents a small proportion of all pancreatic malignancies. Among primary tumors that metastasize to the pancreas, renal cell carcinoma (RCC) is one of the most common causes of metastatic pancreatic lesions. We herein report a case series of three patients with pancreatic metastasis from RCC. The first is a 54-year-old male with a history of left nephrectomy for RCC, in whom an isthmic pancreatic mass suggestive of a neuroendocrine lesion was found during oncological follow-up. Endoscopic ultrasound (EUS)-guided fine needle biopsy (FNB) identified pancreatic metastasis of RCC and the patient was referred for surgery. The second case is a 61-year-old male, hypertensive, diabetic, with left nephrectomy for RCC six years previously, who complained of weight loss and was found with a hyperenhancing mass in the head of the pancreas and a lesion with a similar pattern in the gallbladder. EUS-FNB from the pancreas proved to be a metastatic pancreatic lesion. Cholecystectomy and treatment with tyrosine kinase inhibitors were recommended. The third case is a 68-year-old dialysis patient referred for evaluation of a pancreatic mass, also confirmed by EUS-FNB, who was started on sunitinib treatment. We report a literature summary on epidemiology and clinical features, diagnosis and differential diagnosis and treatment and outcomes in pancreatic metastasis of RCC.

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“…In around 35% of RCC cases, the synchronous metastasis will be present at the time of diagnosis of the primary RCC and about 30% may develop metachronous disease leading to 10% of late diagnosis [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Metastatic renal cell carcinoma involving colon with unusual histologic features and diagnostic challenges: A case report

Saadaat

Haidary

Ibrahimkhil

et al. 2021

International Journal of Surgery Case Reports

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Highlights Metastatic RCC in the colon, although very rare, should be kept in the differential diagnosis of patients with lower GI bleeding, particularly patients with a prior history of kidney mass or nephrectomy Most common type of primary or metastatic RCC is Clear-cell-type. We reported the first case of rhabdoid-RCC metastasizing to colon. In the absence of IHC-stains, rhabdoid-RCC may be misdiagnosed as soft-tissue-sarcoma or other poorly differentiated carcinomas. Our case exclusively occurred in a woman while colonic metastasis of RCC commonly occurring in males.

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Uncommon site of metastasis from renal cell carcinoma: Case report

Abstract: Highlights Renal carcinoma represents 1–3% of visceral malignancies. Metastases of renal tumors may manifest up to a decade after initial injury. Gallbladder represents a rare site of metastatic site, with few reports in the literature.

Cited by 6 publications

References 12 publications

Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

Late Onset of Pancreatic Metastases from Renal Cell Carcinoma. A Case Report

Metastatic Renal Cell Carcinoma to Pancreas: Case Series and Review of the Literature

Metastatic renal cell carcinoma involving colon with unusual histologic features and diagnostic challenges: A case report

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