Uncoupling of Afferent and Myoelectric Reactions in Portions of Gastroduodenal Complex in Acute Damage Period

Abstract

In two series of experiments on cats, afferent reactions of organs of the gastroduodenal complex (gastric corpus, pylorus, and duodenal bulb) were studied and myoelectric activity of these portions of the gastroduodenal complex was examined. In each series, only one portion of the gastroduodenal complex was stimulated with electrical pulses. It was found that processes underlying changes in functional heterogeneity and enhancement or moderation of their interrelations in the acute damage period can affect the development of early regional adaptation.

Functional heterogeneity of damaged gastroduodenal complex

“…During decompensation these correlations strengthen, which reflects moderation of GDC functional heterogeneity, limitation of GDC adaptive potency, and elevation of GDC vulnerability. During acute period, the damage-induced disturbances in the interaction between GDC subdivisions, which result from consolidation of inhibitory processes [7], reflect the basic reaction of immediate adaptation capable to prevent generalization of the pathologic process, thereby improving the adaptive capacity of the integral system.…”