National attention to racial and ethnic health disparities has increased over the last decades, but marked improvements in minority health, especially among children, have been slow to emerge. A life-course perspective with sustained community engagement takes into account root causes of poor health in minority and low-income communities. This perspective involves a variety of primary care, public health, and academic stakeholders. A life-course perspective holds great promise for having a positive impact on health inequities. In this article we provide background information on available tools and resources for engaging with communities. We also offer examples of communityprimary care provider interventions that have had a positive impact on racial and ethnic health disparities. Common elements of these projects are described; additional local and national resources are listed; and future research needs, specifically in communities around issues that are relevant to children, are articulated. Examples throughout the history of pediatrics show the potential to eliminate racial and ethnic health disparities not only for children but also for all populations across the life course. Few topics in health, from individual health care to population health and from social determinants of health 1 to health policy, demand a more comprehensive examination than racial and ethnic health disparities. Health disparities are significant differences in health, health care, and developmental outcomes between populations, to modify a definition from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). National awareness of health disparities has progressed over the last 25 years from the Centers for Disease Control and Prevention 2 (CDC) and the US Department of Health and Human Services 3 reports in the mid1980s to the Institute of Medicine report in 2003,4 but the pace of progress in eliminating these disparities has been slow. 5 In addition, the health-disparities literature tends to focus on mortality, morbidity, and health care interventions related to chronic diseases in adults. This does not mean that little is known about child health disparities, as shown by the annual editions of the Annie E. Casey Foundation's Kids Count Data Book, 6 which review racial and ethnic disparities in child deaths, teen births, infant mortality, and low birth weight, among many other indicators. Furthermore, disparities by race and ethnicity are well documented for childhood asthma, 7 obesity, 8,9 immunizations, 10,11 and health insurance coverage. 12 Health insurance disparities are particularly severe in Latino children. 13 The concept of partnering with communities to improve health is not a new one, especially in the public health world, but it has recently gained momentum in more traditional medical settings as physicians come to realize that all nonbiomedical influences on individual health are not easily addressed in a clinic or hospital room. 14,15 Recent reviews of the literature ...