Unexpected results of a randomized quality improvement program for children with severe asthma

Mosquera, Ricardo A.; Avritscher, Elenir B.C.; Yadav, Aravind; Pedroza, Claudia; Samuels, Cheryl; Harris, Tomika S.; Tetzlaff, Cecilia; Eapen, Julie; Gonzales, Traci; Green, Charles; Tyson, Jon E.

doi:10.1080/02770903.2020.1723621

Cited by 4 publications

(4 citation statements)

References 21 publications

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“…The medication of children with serious illness at home is also a useful medical pattern, which can provide comprehensive and effective care with reducing the medical costs. This new medical way could be an effective way for popularization, especially is appropriate to children with chronic illness, good home medical care can be beneficial to the cure of chronic illness [20]. For the medical pattern of home medical care, much medical treatment is taken at home, parents of children with serious illness also need to spend much time on taking care of those children, which may have large pressure.…”

Section: Literature Reviewmentioning

confidence: 99%

The Medical Saving System of Children With Serious Illness—Base on the Case Study of City X in China

Zhu¹

2020

Proceedings of the 2020 5th International Conference on Humanities Science and Society Development (ICHSSD 2020)

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Medical savings for low income family of children with serious illness is an important issue for all countries. It is required for China to identify an effective medical saving pattern for children with serious illness. The research was undertaken in a city of Guangdong Province in China (it is called 'City X'). Semi-structured interviews and a case study were used in the research. I collected much information from the semi-structured interviews and found that Municipal Civil Affairs Bureau (including Tomorrow Plan Office) offers the list of children with serious illness requiring medical saving, Social Security Department Medical Insurance Division receives the list and offers medical saving fund support and medical security according to the list, these fund support belongs to the government fund support. When the government fund support is not enough, Charity Federation and Chinese Red Cross Foundation will offer additional fund support. China has achieved great improvement on the children with serious illness medical saving institution and system, however two new solutions for collecting more fund for children with serious illness medical saving are still required. The first solution is to issue 'Children with Serious Illness Medical Welfare Lottery'. The winning probability and bonus amount of this welfare lottery can be designed a little higher than the recent welfare lottery and sports lottery to attract more people to purchase. The second solution is to establish 'Extreme Serious Illness Children Medical Welfare Fund'. This fund can be a 'specialized' national fund for 'the children with extreme serious illness', the profit of this fund can be firstly used for the medical saving of 'the children with extreme serious illness without death risk', the bank interest and share these fixed income of this fund can be firstly used for the medical saving of 'the children with extreme serious illness with death risk' because the stability of medical saving fund is crucial to this serious circumstance.

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Section: Literature Reviewmentioning

confidence: 99%

The Medical Saving System of Children With Serious Illness—Base on the Case Study of City X in China

Zhu¹

2020

Proceedings of the 2020 5th International Conference on Humanities Science and Society Development (ICHSSD 2020)

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“… 14 Beyond the financial cost, DA patients’ quality of life and academic performance might suffer dramatically because of the increased risk of exacerbations and hospitalization. 15 , 16 It is anticipated that actively researching efficient treatments for this type of asthma will lessen the significant burden of asthma symptoms worldwide. 17 In this review, we summarize the latest research on the definition and treatment strategy of DA.…”

Section: Introductionmentioning

confidence: 99%

Progress in diagnosis and treatment of difficult-to-treat asthma in children

Zhou,

Zhang,

Tan

et al. 2023

Ther Adv Respir Dis

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At present, medications containing inhaled corticosteroids (ICS-containing) are the keystones of asthma treatment. The majority of asthmatic children can significantly improve clinical outcomes with little worsening by standardized inhaled glucocorticoid treatment, but there is still a small proportion of children who are unable to achieve good symptom control even after the maximum standardized treatment, known as ‘children with difficult-to-treat asthma (DA)’. The high heterogeneity of DA makes therapy challenging and expensive, which poses a serious risk to children’s health and makes it extremely difficult for clinical physicians to accurately identify and treat children with DA. This article reviews the definition, evaluation, and treatment of this asthma in order to provide a reference for optimal clinical decision-making.

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“…Budesonide, a new generation of glucocorticoids, exerts local anti-inflammatory effect and fast onset of action. Thus, it inhibits the production of inflammatory factors, improves the immune system, enhances airway sensitivity to β2 receptors, and promotes functional reconstruction of airway smooth muscle β2 receptors [5]. In Traditional Chinese Medicine (TCM), the pathogenesis of asthma in children is attributed to lung qi impairment and phlegm and qi stasis caused by phlegm due to external pathogens [6].…”

Section: Introductionmentioning

confidence: 99%

Effect of a combination of Tuina therapy and budesonide inhalation on asthma in children, and its influence on lung function and pro inflammatory f actors

Li¹,

Zhang²,

Zhao³

et al. 2022

Trop. J. Pharm Res

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Purpose: To determine the effect of a combination of Tuina therapy and budesonide inhalation on pediatric asthma, and its influence on lung function and levels of inflammatory factors. Methods: Eligible 100 asthmatic children admitted to Provincial Maternity and Child-care Hospital, Lanzhou, Gansu Province, from January 2019 to January 2021 were randomized either to a control group or study group (1:1). The patients in control group were treated with budesonide inhalation, while the study group was given Tuina therapy in combination with budesonide inhalation. Treatment effectiveness, levels of inflammatory factors, immune functions and number of infections were evaluated in the patients. Results: The study group exhibited higher effectiveness profile versus the control group (96 vs 82 %; p < 0.05). After treatment, decreases were observed in the frequency of asthmatic attacks and number of respiratory infections in the two groups, with lower results in the study group than in the control group (p < 0.05). There were marked decreases in the levels of IgG, TNF-α and IL-8 in both groups, with the study group showing higher reductions (p < 0.05). Conclusion: Combined treatment with Tuina and budesonide inhalation decreases the levels of inflammatory factors, regulates immune function, and improves lung function of asthmatic children. Further investigation in a larger population would be required to establish the mechanism and clinical value of this therapy.

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Unexpected results of a randomized quality improvement program for children with severe asthma

Cited by 4 publications

References 21 publications

The Medical Saving System of Children With Serious Illness—Base on the Case Study of City X in China

The Medical Saving System of Children With Serious Illness—Base on the Case Study of City X in China

Progress in diagnosis and treatment of difficult-to-treat asthma in children

Effect of a combination of Tuina therapy and budesonide inhalation on asthma in children, and its influence on lung function and pro inflammatory f actors

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