Unhydrolyzed and hydrolyzed konjac glucomannans modulated cecal and fecal microflora in Balb/c mice

Antioxidative capacity produced by Bifidobacterium‐ and Lactobacillus acidophilus‐mediated fermentations of konjac glucomannan and glucomannan oligosaccharides

“…The growth of B. adolescentis and B. breve increased in the order KGM < KH1 < KH2 at 24 and 48 h. Similarly, the growth of B. longum showed the trend KGM < KH1 ≤ KH2 at 24 and 48 h. Therefore this study agreed with our previous finding that partially hydrolysed glucomannan polysaccharide could stimulate greater Bifidobacterium and L. acidophilus growth than its parent unhydrolysed KGM. 13 The present study further demonstrated that KH2 (DP 5) exerted a greater prebiotic effect than KH1 (DP 10). In addition, we found that KH2 facilitated the growth of B. adolescentis, B. breve, B. bifidum and B. longum to the same extent as OF, while KGM, KH1 and KH2 were better substrates than OF for L. acidophilus.…”

“…13,26 OD 510 values at 6 h were similar among test carbohydrates for each species examined. The growth of B. adolescentis and B. breve increased in the order KGM < KH1 < KH2 at 24 and 48 h. Similarly, the growth of B. longum showed the trend KGM < KH1 ≤ KH2 at 24 and 48 h. Therefore this study agreed with our previous finding that partially hydrolysed glucomannan polysaccharide could stimulate greater Bifidobacterium and L. acidophilus growth than its parent unhydrolysed KGM.…”

“…KGM is a beneficial dietary adjunct for treatment of metabolic syndromes related to free radical damage, such as hypercholesterolaemia, glucose intolerance and diabetes. 11,12 In addition, KGM was recently found to stimulate the growth of bifidobacteria and lactobacilli in both animals 13 and healthy adults.…”

“…In a previous study we demonstrated that a KGM hydrolysate (degree of polymerisation (DP) 12) exerted stronger prebiotic effects than its unhydrolysed parent polymer in Balb/c mice. 13 However, antioxidative effects produced during fermentation of konjac glucomannan of various DP by common intestinal lactic acid bacteria remain to be investigated. Therefore konjac hydrolysate was prepared and fractionated into two oligosaccharide fractions denoted KH1 and KH2, in which the DP of glucomannan was 10 and 5 respectively.…”

Dietary Pulverized Konjac Glucomannan Prevents the Development of Allergic Rhinitis-Like Symptoms and IgE Response in Mice

“…19) Another noteworthy evidence is that acid-hydrolyzed KGM has a greater prebiotic effect than does KGM in increasing cecal and fecal bifidobacteria. 20) This result might provide a mechanistic insight into our observation that PKGM showed a more potent anti-rhinitis effect than did non-pulverized KGM (Fig. 1B).…”