Unified ethical principles and an animal research ‘Helsinki’ declaration as foundations for international collaboration

pH-Responsive and Mucoadhesive Nanoparticles for Enhanced Oral Insulin Delivery: The Effect of Hyaluronic Acid with Different Molecular Weights

“…All animal experiments were approved by the Laboratory Animal Ethics Committee in the Institute of Materia Medica and Peking Union Medical College. All procedures followed ethical standards during the experiment [ 36 ].…”

Visualizing advances in the future of primate neuroscience research

“…Instead, individual institutions, states, and countries ascribe their own ethical standards and regulations with several institutions around the world adopting the NIH guidelines stipulated in the Guide for the Care and Use of Laboratory Animals (https://grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals.pdf) while in Europe, countries adhere to the EU Directive 2010/63/EU. Many neuroscientists involved in NHP research studies are calling for the possibility of a common set of ethical and welfare standards that is internationally acceptable and can lead to international collaborations involving NHP models for the benefit of the monkeys, the scientists, the regulators, the funders, and ultimately the public ( Mitchell et al, 2021 ; Petkov et al, 2022 ). Similarly, global oversight in the form of an international consortium is proposed for biomedical research involving genetically modified monkeys to ensure ethical regulations, NHP welfare, and appropriate training standards are met ( Feng et al, 2020 ).…”

A framework and resource for global collaboration in non-human primate neuroscience

“…Thus, despite this guidance on common standards, NHP researchers interested in pursuing international collaborations still need to adhere to typically multiple, independently formulated guidelines and regulations. An overarching solution would be a unified and agreed upon common set of guidelines, akin to the Helsinki Declaration, but for animal research (see Petkov et al, 2022 ; World Medical Association, 2001 ). In lieu of a common framework that is yet to be formulated, a preliminary step is making national regulations accessible, along with the ethical rationale and models driving these regulations.…”

“…These additional sets of principles could also be incorporated into a common set of guidelines (e.g. see Petkov et al, 2022 ).…”

“…Agreed upon ethical and regulatory standards ensure that international collaborations can flourish ( Mitchell et al, 2021 ). Guidelines that could be used as an international common standard, applicable to other nations, may be available in the form of a general animal welfare declaration ( Petkov et al, 2022 ).…”