Unilateral and segmental cystic disease of the kidney

Punia, Rajpal Singh; Mohan, Harsh; Bal, Amanjit; Bansal, Virender Kumar

doi:10.1111/j.1442-2042.2005.01022.x

Cited by 11 publications

(8 citation statements)

References 6 publications

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“…Morphologically, it resembles ADPKD, which on the contrary shows progression towards renal failure and has extra-renal complications in the form of hepatic and pancreatic cysts, berry aneurysms, aortic dissections and bowel pathologies [9, 10]. In children, autosomal dominant polycystic kidney disease may manifest as localized cystic disease of kidney, but careful history along with radiological examinations of their parents leads to the diagnosis of autosomal dominant polycystic kidney disease.…”

Section: Discussionmentioning

confidence: 99%

Disparate Presentations of Localized Cystic Disease of Kidney: A Review with an Objective of Correct Approach for Accurate Treatment Plan

Khanduri

Chaudhary

Sabharwal

et al. 2017

Cureus

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BackgroundLocalized cystic disease of the kidney is a rare, non-familial condition. Its imaging and clinical features are unique and need to be differentiated from autosomal dominant polycystic kidney disease and focal cystic masses such as multicystic nephroma and cystic renal cell carcinoma. It is always restricted to one kidney and is characterized by multiple cysts of varying sizes separated by residual normal renal tissue.Materials and methodsThis study reports 12 cases of localized cystic disease of the kidney based on imaging findings and clinical histories. The modalities of choice were ultrasonography followed by contrast-enhanced computed tomography. Eight out of 12 patients were men and the average age of presentation was 46 years. The screening of family members and relatives was done to rule out the differentials.ResultsLocalized cystic disease of kidney was diagnosed in all the patients and it presented in two different forms. In three patients, multiple cysts involved whole of the kidney, resulting in thinned-out residual renal parenchyma. In the rest nine patients it remained localised to a particular segment of the kidney. No cysts were observed in the contralateral kidney in seven patients, and one or two simple cysts were observed in five. Clinical presentations included only flank pain in six patients, flank pain with palpable abdominal mass in four patients, two patients presented as asymptomatic cases with diagnosis as an incidental finding and one patient with hematuria. Eight patients underwent imaging and two underwent clinical follow-up for a period of two years showing stability of the disease. One patient underwent nephrectomy for suspected renal neoplasm.ConclusionLocalized cystic disease of the kidney is a unilateral, rare and stable disease that has two different forms of presentations. Its imaging findings should be clearly understood so as to not classify it as a separate disease and avoid unnecessary surgery. It rarely leads to hypertension or polycythemia, and until then no definitive management is required. It can be followed up using imaging techniques and requires nephrectomy only when the suspicion of malignancy is strong.

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Section: Discussionmentioning

confidence: 99%

Disparate Presentations of Localized Cystic Disease of Kidney: A Review with an Objective of Correct Approach for Accurate Treatment Plan

Khanduri

Chaudhary

Sabharwal

et al. 2017

Cureus

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“…However, we still have a limited understanding of segmental MCDK due to the limited number of studies and reports on this disease entity. 2,3,[7][8][9][10][11][12][13][14] Review of previous studies showed M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT 2 that only 39 cases have been reported worldwide, and most were treated by routine surgical resection. Herein, we focused on conservative management of this relatively rare disease by investigation of involution, associated anomalies requiring surgery, and complications of segmental MCDK.…”

Section: Introductionmentioning

confidence: 97%

Conservative Management of Segmental Multicystic Dysplastic Kidney in Children

Han

Lee

Kim

et al. 2015

Urology

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“…Unilateral renal cystic disease (URCD) is a rare disease characterized by cysts with various sizes in a diffusely enlarged kidney without forming a distinct encapsulated mass [1], [2], [3], [4], [5], [6]. Hwang et al reported that the prevalence of URCD in their center was 2.4% [1].…”

Section: Introductionmentioning

confidence: 99%

“…Hwang et al reported that the prevalence of URCD in their center was 2.4% [1]. The differential diagnoses of URCD are autosomal dominant polycystic disease (ADPKD), multilocular cystic renal neoplasms, cystic dysplasia, and multiple simple cysts [1], [5], [7], [8]. It is important to distinguish URCD from ADPKD due to their different outcome [1], [3], [6], [8], [9].…”

Section: Introductionmentioning

confidence: 99%

Unilateral Renal Cystic Disease: A Case Report and Literature Review

Darmadi

Ruslie

Siregar

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: URCD is a rare disease characterized by cysts with various sizes in a diffusely enlarged kidney without forming a distinct encapsulated mass. We present literature review and report a case of URCD in our center. The aim of the study was to report a case of unilateral renal cystic disease (URCD) in a 25-year-old female. CASE REPORT: The patient was a 25-year-old female. She came to emergency unit of Mitra Medika Amplas Hospital Medan, Indonesia, with dyspepsia associated symptoms. Physical examination and family health-related history were normal. Laboratory examinations and genetic evaluation showed no abnormalities. Ultrasonography examination revealed multiple cysts in her right kidney which was confirmed by computed tomography (CT) scan. The diagnosis of URCD was confirmed. No specific treatment was given and she was advised to do a routine follow-up. CONCLUSION: URCD may present with mild symptoms or even asymptomatic. Diagnosis is confirmed by imaging modalities with normal renal function and absence of genetic predisposition. The management is conservative. Routine follow-up is mandatory.

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Unilateral and segmental cystic disease of the kidney

Cited by 11 publications

References 6 publications

Disparate Presentations of Localized Cystic Disease of Kidney: A Review with an Objective of Correct Approach for Accurate Treatment Plan

Disparate Presentations of Localized Cystic Disease of Kidney: A Review with an Objective of Correct Approach for Accurate Treatment Plan

Conservative Management of Segmental Multicystic Dysplastic Kidney in Children

Unilateral Renal Cystic Disease: A Case Report and Literature Review

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