Unilateral Hyperlucency With Left Lower Lobe Mass in a Patient With Bronchial Asthma

Patel, Rajesh G.; Norman, Joe R.

doi:10.1378/chest.107.2.569

Cited by 12 publications

(10 citation statements)

References 11 publications

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“…Although these salivary gland-like neoplasms (SGN) combined account for <0.5% of all primary pulmonary malignancies, 4,5,9,11,16,20 they need to be considered in the cytologic differential diagnosis of lung tumors. The histologic criteria for these neoplasms in the lung have been well documented, [1][2][3][8][9][10][12][13][14][15]18,19,[21][22][23][25][26][27] but cytologic descriptions, especially from bronchial brushing specimens, are fewer. 4,6,20,25 This paper describes three primary mucoepidermoid carcinomas and one primary adenoid cystic carcinoma of the lung that were diagnosed from cytologic specimens.…”

mentioning

confidence: 99%

Cytology of Primary Pulmonary Mucoepidermoid and Adenoid Cystic Carcinoma

Segletes¹,

Steffee²,

Geisinger³

1999

Acta Cytologica

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mentioning

confidence: 99%

Cytology of Primary Pulmonary Mucoepidermoid and Adenoid Cystic Carcinoma

Segletes¹,

Steffee²,

Geisinger³

1999

Acta Cytologica

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“…Mucoepidermoid tumors of the lung are the rarest variants of bronchial adenomas, being slightly more common in female patients (11,12). These lesions are believed to arise from the excretory ducts of the submucosal bronchial glands, and are located in the main stem bronchus or proximal portion of a lobar bronchus (11,13,14). Symptoms, when present, are due to partial or complete airway obstruction and include cough, wheezing, and dyspnea.…”

Section: Discussionmentioning

confidence: 99%

“…Chest radiographs may show nodular masses, areas of lung consolidation, and partial or complete atelectasis (15). Because no characteristic features distinguish these tumors from bronchogenic carcinoma and other benign lesions, bronchoscopy and biopsy are especially helpful in establishing the diagnosis (14,16). Mucoepidermoid carcinoma of the lung (formally called bronchial adenoma) consists 5% to 10% of these tumors (17,18).…”

Section: Discussionmentioning

confidence: 99%

Mucoepidermoid Carcinoma (MEC): A Rare Cause of Chronic Cough in Children

et al. 2013

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Introduction: Bronchial adenoma is rare in primary tumors of the lung and produce non-specific respiratory symptoms. Case Presentation: A 4-year-old boy referred to our clinic with chronic cough and wheezing. Foreign body aspiration was recommended for him on the base of radiologic and clinical manifestation. In bronchoscopy, foreign body was not detected, but an obstructing tumor was found at left lower lobe bronchial orifice. Trans bronchial biopsy, revealed a histopathologically low grade mucoepidermoid carcinoma. He underwent left lower lobectomy with safe margin. Conclusions: However, respiratory tract tumors are rare in children but can masquerade foreign body in this group. We suggest that in children of recurrent pneumonia with persistent lung infiltration, bronchial tumor should be considered.

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“…Children are usually diagnosed following recurrent pneumonias [8,9,[14][15][16], persistent cough [1,9,11], and/or wheezing (not responding to bronchodilator therapy) [4,7,8,11,17]. Some younger children may be misdiagnosed as new-onset asthma [10].…”

Section: Discussionmentioning

confidence: 99%

“…Some younger children may be misdiagnosed as new-onset asthma [10]. Other children present with atelectasis by complete or partial airway obstruction or with unilateral hyperlucent lungs [14,17]. MEC infrequently presents with haemoptysis [16].…”

Section: Discussionmentioning

confidence: 99%

An 11-yr-old male with pneumonia and persistent airway obstruction

Niggemann

Gerstner²,

Guschmann³

et al. 2002

Eur Respir J

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Case reportAt the age of 4 yrs the male child suffered from a Wilms-tumour of the right kidney treated by polychemotherapy (SIOP No. 9 for stage 1 using actinomycin and vincristin) and surgical removal. A year later, abdominal pain occurred and a local relapse of the Wilms-tumour was diagnosed. Further diagnostics revealed infiltration into the liver, diaphragm, and the thoracic wall. In addition, three lung metastases were found. The child received polychemotherapy again (according to protocol SIOP 93/01 for stage 4 using adriamycin, etoposide, carboplatin, ifosphamide) and radiotherapy of the lung, abdomen (15 Gray) and of the tumour site (35 Gray). The tumour could be resected. All follow-ups during the next 6 yrs showed remission and the child was healthy.At the age of 11 yrs, he presented with fever and cough. The chest radiograph showed an opacity of the left upper field ( fig. 1). Under the suspicion of pneumonia, antibiotic treatment was started. Due to bronchial obstruction, the child received low-dose inhaled steroids and b-adrenergic agents. Nonetheless, he still suffered from bronchial obstruction and intermittent fever. Pulmonary function measurement revealed a mixed restrictive and obstructive ventilation disorder (forced vital capacity 52%, forced expiratory volume in one second 49% and flow at 25% vital capacity 13% predicted). Computed tomography (CT) scan of the thorax (including radioopaque material) was performed ( fig. 2).For further diagnosis flexible bronchoscopy was performed, revealing a ball-shaped, soft, solid tumour deriving from the left upper lobe bronchus and bulging into the ostium of the left main bronchus ( fig. 3). In order to obtain a thorough diagnosis of the tumour, thoracic surgical intervention was performed. The histology of the tumour revealed typical findings ( fig. 4).

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Unilateral Hyperlucency With Left Lower Lobe Mass in a Patient With Bronchial Asthma

Cited by 12 publications

References 11 publications

Cytology of Primary Pulmonary Mucoepidermoid and Adenoid Cystic Carcinoma

Cytology of Primary Pulmonary Mucoepidermoid and Adenoid Cystic Carcinoma

Mucoepidermoid Carcinoma (MEC): A Rare Cause of Chronic Cough in Children

An 11-yr-old male with pneumonia and persistent airway obstruction

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