Unilateral juvenile hypertrophy of the breast

Rapid, massive and unphysiological breast enlargement

“…Thick intralobular fibrous stroma loosely arranged are particularly abundant with bands of dense collagenous tissue and occasional lymphocytes. There may be calcification resulting from necrotic degeneration [84].…”

“…The incidence has been reported at two in 56794 deliveries, and is probably less than one in 100000 [7]. It is usually bilateral but has been reported as unilateral in three cases [35,84,110]. This condition can be life-threatening, requiring emergency bilateral mastectomy.…”

“…Frequently, it occurs in multigravida women without problems in previous pregnancies [2,7,8,10,12,15,20,22,23,33,35,46,49,60,62,70,72,75,77,78,83,84,90,97,98,109,110,113,119], but it has been reported in first pregnancies [7,11,13,15,35,44,57,64,65,73,83,88,99,106,108,111,116,121,122,124].…”

“…It is then necessary to perform later reduction mammoplasty [7,10,20,60,75,78,99,122] with free nipple grafts [60,99,122], staged mastectomy [62], subcutaneous or simple mastectomy [10,13,35,72,73,84,88,90,113] with nipples banked in the groins [88], eventually followed by reconstruction with silicone implants [10,84,88,113]. Total mastectomy is preferred as the condition is likely to recur, complicating all subsequent pregnancies [7,12,77,78,83,88,109].…”