Unilateral nasal pain with migraine features

Abstract

Migraine pain mostly develops within the innervation territory of the first branch of the trigeminal nerve, which includes the nose. Therefore, episodes of unilateral nasal pain with migrainous features could be considered a migraine with unusual topography (nasal migraine). Painful nasal attacks occasionally preceded by stimulation of trigeminal afferents in the nose, could be conceived of as migraine-tic syndrome.

Sneezing in Primary Headaches With Cranial Autonomic Symptoms: Pathophysiological Considerations. A Series of Case Reports

“…Sneezing could also induce indomethacin‐responsive headaches with cranial autonomic symptoms . Alvarez et al described a case of “nasal migraine” starting with a tingling sensation in the nasal vestibule typical recognized as a premonitory feeling of sneezing …”

“…14 Alvarez et al described a case of "nasal migraine" starting with a tingling sensation in the nasal vestibule typical recognized as a premonitory feeling of sneezing. 15 The pathophysiology of sneezing in primary headaches suggests a peripheral or central activation. In our case reports, a peripheral activation is a hypothesis, with stimulation of one of the trigeminal nerve branch, in response to cranial autonomic symptoms (as tearing or rhinorrhea).…”

Atypical Nummular Headache or Circumscribed Migraine: The Utility of Pressure Algometry

“…Contrary to characteristics suggesting a peripheral origin of NH, some data tend to support a central origin of NH in some patients, such as multifocal descriptions or pain reappearance in another area after removal of symptomatic NH scalp ( 4 ). On the other hand, the occurrence of migraine in a single location has been described, mainly around the eyes, or in the frontal or temporal scalp ( 12 , 13 ).…”

External Nasal Neuralgia: A Neuropathic Pain Within the Territory of the External Nasal Nerve

“…Besides, the episodes had a daily appearance and did not last longer than 30 minutes. Consequently, a nasal migraine can be discarded as a likely diagnosis …”

“…Apart from nose and sinus disorders – namely, traumatisms, infections, or neoplastic lesions in the bones, cartilages, mucosae, or skin – nasal pain may originate from painful cranial neuropathies or other neurological conditions whose pathophysiology presumably has a central cause, such as nasal migraine or idiopathic rhinalgia . Certainly, cranial neuralgias may account for a noteworthy number of patients experiencing nasal pain.…”