A c c e p t e d M a n u s c r i p t 2 Bartonella henselae neuroretinitis in patients without cat scratch SUMMARY Cat-scratch disease (CSD) is a syndrome which is characterized by lymphadenopathy, fever, and skin lesions in association with a cat scratch or bite. Bartonella henselae is the primary bacterial agent responsible for CSD. Here we report serologically proven atypical presentation cases of B henselae neuroretinitis. In this study, three neuroretinitis patients were evaluated.Animal contact histories, ocular examinations, systemic work-up, clinical findings, and treatment compliance of the patients were assessed. All the patients denied a history of a cat or any animal contact, or of having CSD findings. Serologic testing with indirect immunofluorescence assay (IFA) was used for diagnosis of Bartonella neuroretinitis. IFA test results were positive for all patients. Two of the patients were treated with antibiotics. Optic disc edema and macular exudates resolved gradually, and at their last follow-up visits, all the signs had disappeared. There was no disease recurrence after finishing treatment. Serious complications were seen in the untreated patient. In conclusion, even though there may be a lack of systemic signs and symptoms of CSD in a patient with neuroretinitis, B henselae infection should be considered.