Unilateral Peripapillary Myelinated Nerve Fibers With Myopia and/or Amblyopia

Hittner, Helen Mintz; Antoszyk, James H.

doi:10.1001/archopht.1987.01060070079033

Cited by 37 publications

(17 citation statements)

References 28 publications

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“…Wide spread MNF is associated with increased degrees of myopia [6]. Visual impairment of the patients may be the result of anisometropic amblyopia or may be secondary to coexistent pathology, such as macular pucker, macular pigment dispersion, and an abnormal macular reflex [7,8]. Despite refractive correction and amblyopic therapy, many such patients do not respond well to treatment [2].…”

Section: Discussionsupporting

confidence: 41%

The results of electrophysiological tests in unilateral extensive peripapillary myelinated nerve fibers: report of three cases

et al. 2009

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The purpose of this study is to describe clinical and electrophysiological findings of three patients with unilateral extensive peripapillary myelinated nerve fibers. Three patients with unilateral extensive peripapillary myelinated nerve fibers were examined. A complete ophthalmologic examination including uncorrected and best spectacle corrected visual acuities (UCVA, BSCVA) on Snellen charts, dilated fundoscopy, fundus fluorescein angiography (FFA), optical coherence tomography (OCT), perimetry and electrophysiological tests was performed. ERG results of both eyes were normal in all cases. FFA showed hypofluorescence at the myelinated nerve fibers (MNF) area in the affected eyes. We found a visual field defect resembling arcuat scotom at perimetry of the affected eyes. In OCT, there was hyper-reflectivity in reply to MNF. In all cases, pattern ERG results of the affected eyes showed decreased amplitudes and increased latencies of P50 and N95 waves. P100 amplitudes of PVER and FVER were decreased, and latencies were increased in all affected eyes. Extensive peripapillary myelinated nerve fibers may cause changes in PERG and VER.

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Section: Discussionsupporting

confidence: 41%

The results of electrophysiological tests in unilateral extensive peripapillary myelinated nerve fibers: report of three cases

et al. 2009

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“…[3][4][5]8 Kee and Hwang 4 found that in only one third of eyes with myelinated nerve fibers visual acuity improved to 20/30 or better. The amount of anisometropia and the extent of myelinated nerve fibers were negatively correlated with final visual acuity.…”

Section: Discussionmentioning

confidence: 43%

Myelinated retinal nerve fibers associated with hyperopia and amblyopia

Lee

Salchow

2008

Journal of American Association for Pediatric Ophthalmology and

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“…Kasmann et al reported similar results in 4 cases [17]. Hittner et al reported that 5 out of 12 patients with MRNF had good visual acuity [18]. Straatsma et al suggested that younger patients who have parafoveal fixation and no strabismus respond best to amblyopia therapy, and advocated earlier therapy to treat the amblyopia associated with MRNFs [19].…”

Section: Discussionsupporting

confidence: 39%