Unilateral superior pellucid marginal degeneration in a case with ichthyosis

Dündar, Hüseyin; Kara, Necip; Kaya, Vedat; Bozkurt, Ercüment; Yazıcı, Ahmet; Hekimhan, Pelin Kaynak

doi:10.1016/j.clae.2010.09.001

Cited by 10 publications

(7 citation statements)

References 27 publications

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“…This case may be an atypical type of PMCD, which was consistent with previous reports as unilateral PMCD 4,5 or superior PMCD. [5][6][7] To the best of our knowledge, this is the first case report of spontaneous lower conjunctival bleb formation in a patient with presumed PMCD with acute hydrops. The pathogenesis was documented by OCT images, which provided useful information for diagnosis and treatment.…”

Section: Discussionmentioning

confidence: 76%

Spontaneous Bleb Formation in a Presumed Pellucid Marginal Corneal Degeneration With Acute Hydrops

Toriyama

Suzuki²,

Higashiura³

et al. 2013

Cornea

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Section: Discussionmentioning

confidence: 76%

Spontaneous Bleb Formation in a Presumed Pellucid Marginal Corneal Degeneration With Acute Hydrops

Toriyama

Suzuki²,

Higashiura³

et al. 2013

Cornea

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“…iktiyozisli bir olguda ters PMD tespit etmişlerdir. 2 Ertan, Lang, Bower ve Taglia ters PMD olguları sunmuşlardır.…”

Section: Discussionunclassified

Reverse Pellucid Marginal Degeneration

Kaya¹,

Acar²,

Gürdal³

2019

Turkiye Klinikleri J Ophthalmol

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“…Based on the published literature, true PMD is clinical PMD with typical inferior corneal thinning. 4 , 5 , 6 , 7 , 8 , 37 This thinning process is absolutely time-consuming and does not occur suddenly. The PMD cases presented in the published articles are severe cases of PMD, fail to describe the classification for PMD, 4 , 5 , 6 , 7 , 8 , 37 and now the question is what is the topographic/tomographic pattern in the early stage of PMD.…”

Section: Discussionmentioning

confidence: 99%

“…The area superior to the thinned part is ectatic, and the area between the limbus and thinned part is clear, without any scarring, lipid deposition, or vascularization. 2 Although PMD is localized as a bilateral inferior condition, its other features such as superior, 3 unilateral 4 or a combination of them 5 have also been reported. A typical topographic map in PMD shows flattening in the vertical meridian with marked against-the-rule astigmatism.…”

Section: Introductionmentioning

confidence: 99%

Corneal hysteresis and corneal resistance factor in pellucid marginal degeneration

Sedaghat

Ostadi-Moghadam

Jabbarvand

et al. 2018

Journal of Current Ophthalmology

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PurposeTo evaluate and compare corneal hysteresis (CH) and corneal resistance factor (CRF) in pellucid marginal degeneration (PMD), keratoconus (KCN), and normal eyes using the Ocular Response Analyzer (ORA).MethodsIn this retrospective study, corneal biomechanical parameters were measured in patients with PMD (n = 102) and KCN (n = 202) and normal subjects (n = 208) using the ORA. Data, including full patient history as well as the results of refraction, slit-lamp biomicroscopy, Pentacam HR (Oculus), and ORA (Reichert; Buffalo, New York, USA), were collected from medical records. Also, the data of only one eye per individual were selected for the analysis. The inclusion criteria for PMD and KCN groups were a reliable diagnosis of these ectatic disorders based on the clinical and corneal tomographic findings. CH, CRF, CH–CRF, intraocular pressure (IOP) measurements were assessed for each subject. Data were analyzed with SPSS and MedCalc using the ANOVA, Pearson Correlation, and receiver operating characteristic (ROC) curve analysis.ResultsThe mean CH was 8.91 mmHg ± 1.05 [standard deviation (SD)], 8.43 ± 0.78, and 10.89 ± 1.08 in the PMD, KCN, and normal group, respectively. Also, the mean CRF was 8.21 ± 1.35, 7.19 ± 1.11, and 10.69 ± 1.41 in the PMD, KCN, and normal group, respectively. ANOVA showed differences in the mean CH, CRF, and CH–CRF between three groups (P < 0.001). Also, ROC curve analysis showed the cut-off points ≤9.5, ≤9.5, and >1.3 mmHg for CH, CRF, and CH–CRF in the PMD group, respectively. For biomechanical parameters in PMD eyes, CRF had the highest sensitivity (75.49%) while the greatest area under the ROC curve (AUC) was seen for CH (0.903). Moreover, central corneal thickness (CCT) showed no correlation with CH (P = 0.30, r = −0.104) or CRF (P = 0.75, r = 0.033) in the PMD group.ConclusionsThis study presented the values of corneal biomechanics for PMD using the ORA. The results of the ORA were markedly different between PMD, KCN, and normal eyes.

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Unilateral superior pellucid marginal degeneration in a case with ichthyosis

Cited by 10 publications

References 27 publications

Spontaneous Bleb Formation in a Presumed Pellucid Marginal Corneal Degeneration With Acute Hydrops

Spontaneous Bleb Formation in a Presumed Pellucid Marginal Corneal Degeneration With Acute Hydrops

Reverse Pellucid Marginal Degeneration

Corneal hysteresis and corneal resistance factor in pellucid marginal degeneration

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