Up to one-third of patients undergoing transcatheter aortic valve implantation (TAVI) have also an indication for long-term anticoagulation. 1 In this kind of patients, a thorough evaluation of bleeding and ischemic risks is important to decide the best peri-and postprocedural anticoagulation therapy. Traditionally, oral anticoagulation (OAC) is usually uninterrupted during peri-procedural