Unique G4-nanowires-mediated switch-modulated electrochemical biosensing for sensitive detection of nickel ion and histidine

A water-soluble copper-immobilized covalent organic framework functioning as an “OFF–ON” fluorescent sensor for amino acids

“…Several analytic techniques have been reported previously for the quantitative detection of Cys and L-His, including those based on UV-Vis absorption spectroscopy, electrochemical analysis, capillary electrophoresis, spectrofluorimetry, immunoassaying, and high-performance liquid chromatography (HPLC). [15][16][17][18][19][20][21] These techniques, however, have various shortcomings: they can be time-consuming and/or operationally inconvenient, and they can require cumbersome and/or expensive instruments. Recently, photophysical analytical techniques, particularly fluorescence-based versions, have become widespread for their high sensitivity, low detection limits, low cost, convenience, and suitability for bioimaging.…”

Reconfigurable Implication and Inhibition Boolean logic gates based on NAD+‐dependent enzymes: Application to signal‐controlled biofuel cells and molecule release

“…[17] While some of the logic gates particularly OR, AND gates, were studied in numerous versions for different applications, some other Boolean functions were modeled rarely. Particularly, Implication (IMPLY) logic operation, suggested more than a hundred years ago as an essential logic gate, [18] was understudied and its molecule realization has been reported only recently using various chemical (not bio-) systems [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] and in DNA-based systems, [34][35][36][37][38][39][40][41][42][43][44][45] particularly operating in cellular processes. [46] Enzyme-based systems mimicking the IMPLY logic gate have been reported only in very few recent papers.…”

An overview of Structured Biosensors for Metal Ions Determination

“…The interaction of gold with thiol groups via a redox reaction led to a self-assembled monolayer on the metallic surface, resulting in the deposition of gold thiolates [189]. The execution of simple steps such as dip and drop coatings allowed for an easy immobilization of the naturally or synthetically thiolated molecules, such as peptides and DNA strands, after 2 to 12 h of contact with the surface [9,26,36,37,42,44,59,73,98,119,124,127,133,140,143,144,153,156,158,164,165,[167][168][169]172,176]. Alternatively, the gold layer was modified with mercaptohexanol [134,168], hexanethiol [159], and aminothiophenol [154,155] to immobilize the target molecules and nanoparticles.…”

“…Mainly, biosensors show lower costs of acquisition and maintenance, lower detection limits without prolonged sample preparation steps, and adequate selectivity [26]. In many cases, biosensors have been applied to the accurate determination of elements at trace and ultra-trace levels [25].…”