Unloaded Movement Facilitation Exercise Compared to No Exercise or Alternative Therapy on Outcomes for People with Nonspecific Chronic Low Back Pain: A Systematic Review

Slade, Susan C; Keating, Jennifer Lyn

doi:10.1016/j.jmpt.2007.03.010

Cited by 68 publications

(50 citation statements)

References 61 publications

(79 reference statements)

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“…36,37 However, neither nonsurgical nor surgical therapy restore functional native disk tissue, or regenerate the degenerated disk tissue, resulting in chronic inflammatory pain. Therefore, attempts are being made to seek effective biological alternatives so that the damaged tissue can be recovered both in structure and functionality.…”

Section: Discussionmentioning

confidence: 99%

Antioxidative nanofullerol prevents intervertebral disk degeneration

Yang¹,

Jin²,

Lu³

et al. 2014

IJN

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Compelling evidence suggests that reactive oxygen species (ROS) play a pivotal role in disk degeneration. Fullerol nanoparticles prepared in aqueous solution have been demonstrated to have outstanding ability to scavenge ROS. In this report, in vitro and in vivo models were used to study the efficacy of fullerol in preventing disk degeneration. For in vitro experiments, a pro-oxidant H 2 O 2 or an inflammatory cytokine interleukin (IL)-1β was employed to induce degenerated phenotypes in human nucleus pulposus cells encapsulated in alginate beads, and fullerol was added in the culture medium. For the animal study, an annulus-puncture model with rabbit was created, and fullerol was injected into disks. It was shown that cytotoxicity and cellular ROS level induced by H 2 O 2 were significantly diminished by fullerol. IL-1β-induced nitric oxide generation in culture medium was suppressed by fullerol as well. Gene-profile and biochemical assays showed that fullerol effectively reversed the matrix degradation caused by either H 2 O 2 or IL-1β. The animal study delineated that intradiskal injection of fullerol prevented disk degeneration, increasing water and proteoglycan content and inhibiting ectopic bone formation. These results suggest that antioxidative fullerol may have a potential therapeutic application for disk degeneration.

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Section: Discussionmentioning

confidence: 99%

Antioxidative nanofullerol prevents intervertebral disk degeneration

Yang¹,

Jin²,

Lu³

et al. 2014

IJN

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“…A number of systematic reviews, which relate to MDT for low back pain, attest to its evidence base. There is evidence supporting the efficacy of MDT in acute to chronic low back pain [2][3][4][5][6][7] ; the prognostic validity of a key feature of the system, which is centralization 8 ; and the greater reliability of the MDT assessment process compared to other methods. 9 The application of the system to extremity as opposed to spinal musculoskeletal symptoms was published more recently.…”

mentioning

confidence: 99%

The McKenzie Classification System in the Extremities: A Reliability Study Using Mckenzie Assessment Forms and Experienced Clinicians

May

Ross

2009

Journal of Manipulative and Physiological Therapeutics

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“…Twenty-one articles 1,6,8,9,[12][13][14][15][20][21][22]24,25,28,33,[38][39][40][42][43][44] were selected for further evaluation. Thirteen reviews 1,6,9,13,15,[20][21][22]38,39,[42][43][44] were eliminated after further evaluation. Reasons for exclusion included assessed outcomes that were not disability or pain in 1 review, 20 interventions that were not focused on specific stabilization exercises in 8 reviews, 9,15,21,38,39,[42][43][44] and the lack of an SR format in 1 review.…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen reviews 1,6,9,13,15,[20][21][22]38,39,[42][43][44] were eliminated after further evaluation. Reasons for exclusion included assessed outcomes that were not disability or pain in 1 review, 20 interventions that were not focused on specific stabilization exercises in 8 reviews, 9,15,21,38,39,[42][43][44] and the lack of an SR format in 1 review. 22 Additionally, 2 reviews were practice guidelines, 1,6 and 1 13 was a duplication of findings published in another review.…”

Section: Resultsmentioning

confidence: 99%

Quality of Systematic Reviews on Specific Spinal Stabilization Exercise for Chronic Low Back Pain

Haladay¹,

Miller

Challis

et al. 2013

Journal of Orthopaedic & Sports Physical Therapy

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Study Design Systematic literature review. Objective To evaluate the quality of systematic reviews (SRs) on specific stabilization exercises for chronic low back pain (LBP). Background Multiple SRs regarding the effectiveness of lumbar stabilization exercises for people with chronic LBP have been published. As more SRs are published, the more it is recognized that, like other forms of research, methodological quality affects the validity of, and conclusions drawn from, the data. Methods A search of MEDLINE, CINAHL, and Embase was completed. Additionally, the PEDro database was screened and hand searching was completed. Included SRs had to contain randomized controlled trials examining a specific stabilization exercise program for the treatment of chronic LBP. Additionally, the assessed outcome measures had to include pain and/or disability measures. Literature reviews and clinical practice guidelines were excluded. Three reviewers independently assessed each SR for methodological quality. Results The search produced 665 SRs for review, of which 8 fulfilled the inclusion criteria. Consensus quality assessment scores ranged from 13/26 to 26/26, with an average of 20.7 points. Percent agreement and kappa values for individual criteria scores ranged from 50% to 92% and 0.25 to 0.85, respectively. Agreement was moderate to substantial across individual items, except for criterion 1. The intraclass correlation coefficient for overall score was 0.98 (95% confidence interval: 0.96, 0.99). Conclusion This review of SRs identified several high-quality reviews that indicated some benefit of specific stabilization exercise programs for patients with nonspecific chronic LBP. Level of Evidence Therapy, level 1a. J Orthop Sports Phys Ther 2013;43(4):242–250. Epub 14 January 2013. doi:10.2519/jospt.2013.4346

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Unloaded Movement Facilitation Exercise Compared to No Exercise or Alternative Therapy on Outcomes for People with Nonspecific Chronic Low Back Pain: A Systematic Review

Cited by 68 publications

References 61 publications

Antioxidative nanofullerol prevents intervertebral disk degeneration

Antioxidative nanofullerol prevents intervertebral disk degeneration

The McKenzie Classification System in the Extremities: A Reliability Study Using Mckenzie Assessment Forms and Experienced Clinicians

Quality of Systematic Reviews on Specific Spinal Stabilization Exercise for Chronic Low Back Pain

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