Unresectable pancreatic adenocarcinoma: do we know who survives?

Abstract

A simple and clinically meaningful point-based symptom score can successfully predict survival in patients with UPA.

Survival and clinical outcome after endoscopic duodenal stent placement for malignant gastric outlet obstruction: comparison of pancreatic cancer and nonpancreatic cancer

“…Müller et al 27 found that American Society of Anesthesiologists score, the presence of liver metastasis, pain, CA19-9, and carcinoembryonic antigen levels were independent predictors of poor survival in patients undergoing bypass surgery for GOO due to pancreatic cancer. Finally, Jamal et al 29 proposed a McGill-Brisbane score based on weight loss of more than 10% of body weight, pain, jaundice, and smoking as a predictor of survival to tailor palliative treatment. However, given that the majority of these studies investigated factors predictive of overall survival rather than post-stent placement survival, the findings may not be perfectly relevant to our patients.…”

Pancreatic cancer and predictors of survival: comparing the CA 19-9/bilirubin ratio with the McGill Brisbane Symptom Score

“…If patients were not reported as deceased, they were censored on 14 February 2011, allowing a minimum of 14‐month follow‐up for the last patients included in this study. The primary outcome of this study was mortality at 9 months, a clinically significant endpoint based on previous studies . Overall survival was also assessed.…”

“…Upon presentation, 80% of patients have locally advanced or metastatic disease and are not immediate surgical candidates . Predicting survival in patients who have resectable and unresectable PAC is a crucial step in optimizing personalized patient management …”

“…However, any concomitant infectious process might yield falsely elevated scores. The McGill surgical department has published and validated a new symptom‐based score that accurately identifies PAC patients at baseline who will have increased survival, in both resected and unresected groups . The McGill Brisbane Scoring System (MBSS) is assessed at the time of first encounter and is based on smoking status, pain, jaundice and a reported weight loss of more than 10% (Table ).…”

Influence of cachexia and sarcopenia on survival in pancreatic ductal adenocarcinoma: A systematic review

“…Their model included weight loss more than 10%, jaundice, pain and smoking and was able to discriminate those with worse life expectation better than imaging. Weight loss >10% was the best independent predictor of low survival providing 38% of the final score [20].…”