2020
DOI: 10.1109/jbhi.2019.2951024
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Unsupervised 3D End-to-End Medical Image Registration With Volume Tweening Network

Abstract: 3D medical image registration is of great clinical importance. However, supervised learning methods require a large amount of accurately annotated corresponding control points (or morphing), which are very difficult to obtain. Unsupervised learning methods ease the burden of manual annotation by exploiting unlabeled data without supervision. In this paper, we propose a new unsupervised learning method using convolutional neural networks under an end-to-end framework, Volume Tweening Network (VTN), for 3D medic… Show more

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Cited by 243 publications
(203 citation statements)
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“…The regularization parameter of VoxelMorph is 4. For RCN, we used Volume Tweening Network (VTN) [38] as basic network architecture. RCN also contains four subnetworks: an affine network and three deformable registration subnetworks.…”
Section: F Baseline Methodsmentioning
confidence: 99%
“…The regularization parameter of VoxelMorph is 4. For RCN, we used Volume Tweening Network (VTN) [38] as basic network architecture. RCN also contains four subnetworks: an affine network and three deformable registration subnetworks.…”
Section: F Baseline Methodsmentioning
confidence: 99%
“…To warp the moving image only once, so as to reduce the influence of multiple interpolations on image quality and registration accuracy, affine transformation parameters are required to calculate the DVF expressed by u a through applying transformation using the parameters on an initial DVF. u a and u d are further aggregated through the way proposed by Zhao et al [28] to yield the final DVF denoted as u f , with which the moving image is warped through a spatial transformer to yield the final registration result. The parameters Ξ indicate the kernel values of convolutional layers that are updated by iterative optimization.…”
Section: Methodsmentioning
confidence: 99%
“…Zhou et al [ 110 ] proposed 3D CNN for serial electron microscopy images (experiments were performed on two databases, Cremi and FIB25) registration. Recently, Zhao et al [ 111 ] presented a 3D Volume Tweening Network (VTN) for 3D medical image (liver CT and brain MRI dataset) registration in an unsupervised manner. Compared to the traditional optimization approaches (ANTs [ 107 ], Elastix [ 112 ] and VoxelMorph-2 [ 113 ]), their method was 880 times faster, with state-of-the-art performance.…”
Section: Applications In 3d Medical Imagingmentioning
confidence: 99%