1985
DOI: 10.1288/00005537-198512000-00005
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Untoward sequelae of prolonged intubation

Abstract: Laryngeal sequelae following prolonged endotracheal intubation are being observed with increasing frequency as this technique of airway management is being employed for extended periods of time. Many etiologic factors have been implicated in the development of these problems with the exact reasons being as yet unknown. After reviewing the records of 372 consecutive patients intubated over an 18-month period, we have observed an increased frequency of these complications in the diabetic female patient and sugge… Show more

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Cited by 88 publications
(70 citation statements)
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“…The presence of comorbidities, such as diabetes mellitus, gastroesophageal reflux, and immunosuppression, have also been shown to predispose patients to develop stenosis. 17,20,78,79 Therefore, this population would perhaps benefit from early tracheotomy. 78 The reported historical incidence of laryngotracheal stenosis after endotracheal intubation ranges from 1 to 21%, 76,80 but it is hoped that increasing knowledge about how to limit airway injury from prolonged intubation will reduce these rates.…”
Section: Larynxmentioning
confidence: 99%
“…The presence of comorbidities, such as diabetes mellitus, gastroesophageal reflux, and immunosuppression, have also been shown to predispose patients to develop stenosis. 17,20,78,79 Therefore, this population would perhaps benefit from early tracheotomy. 78 The reported historical incidence of laryngotracheal stenosis after endotracheal intubation ranges from 1 to 21%, 76,80 but it is hoped that increasing knowledge about how to limit airway injury from prolonged intubation will reduce these rates.…”
Section: Larynxmentioning
confidence: 99%
“…Prolonged intubation, or intubation occurring for more than 4 days [2], is commonly associated with some serious but oftentimes mild complications. One such mild complaint, tongue swelling, is ubiquitous for those undergoing surgical procedures and has previously been reported [3][4][5].…”
Section: Discussionmentioning
confidence: 99%
“…Patients may also present with apparent lingual swelling after extubation due to sialadenitis from submandibular duct obstruction by the endotracheal tube or traumatic intubation causing a sublingual hematoma [7,8]. Other mild complications of prolonged intubation include difficulty with phonation and dysphagia after extubation [9], while more serious complications include laryngeal injury and upper airway distress requiring advanced airway management [2,10]. Ischemic necrosis of the tongue in intubated patients is rare and previously reported in patients with cardiogenic shock requiring pressor support or those undergoing prolonged neurosurgical or head and neck surgeries [11,12].…”
Section: Discussionmentioning
confidence: 99%
“…When pressure from the firm walls of the tube exceeds capillary pressure in the mucosa of the larynx, mucosal ischemia causes pain, swelling, and redness within the first few hours (Gaynor and Greenberg, 1985). 3 Capillary perfusion pressure is the critical concern in mucosal injury -ischemic necrosis gives rise to epithelial damage and ulceration, the basic lesions from which complications occur (Weymuller, 1988).…”
Section: Pathogenesismentioning
confidence: 99%