Unusual presentations of Comamonas kerstersii infection

Abstract

The association of Comamonas kerstersii with peritonitis resulting from the presence of perforated appendix has previously been described by our research team. In the present study, we describe the isolation of this microorganism from two forms of unusual presentations of C. kerstersii infection not previously described in the literature: localized intra-abdominal infection (psoas abscess) and pelvic peritonitis.

Difficulties in Identification of Сomamonas Kerstersii Strains Isolated From Intestinal Microbiota of Residents of Republic of Guinea and Russian Federation

“…kerstersii strains were isolated from patients with catheter-associated infections (bacteremia), peritonitis, appendicitis, postoperative complications in the form of septic infections, meningitis, etc. In Argentina in 2010-2015 C. kerstersii in association with other opportunistic microorganisms were isolated from the psoas abscess, and in a case of pelvic peritonitis, from the abdominal fluid in 12 patients with acute peritonitis that developed as a result of gangrenous or perforated appendicitis [4,5]. In the UK for two years, C. kerstersii were isolated from 27 hospitalized patients with diarrhea.…”

“…As the databases expand, the identification capacity of the methods will include a wider range of microorganisms, and other types of Сomamonas. Publications about etiological significance of C. kerstersii appeared shortly after the method of Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) mass spectrometry was used to identify microorganisms in bacteriological laboratories and the reliability of the identification results was confirmed by molecular genetic methods [4,5,8,17].…”

“…The data of a few foreign studies of the antimicrobial susceptibility testing of C. kerstersii strains do not allow comparison of the results, as some authors used a disc-diffusion method (not recommended by CLSI) for testing these microorganisms [8] or testing using other interpretation criteria [4,5]. Nevertheless, the MIC results allow us to conclude that resistance to fluoroquinolones, trimethoprim/ sulfamethoxazole and amikacin was noted among C. kerstersii strains isolated at different times [4,5,17]. Our results confirm the high in vitro activity of the expanded spectrum cephalosporins, carbapenems, aminoglycosides and chloramphenicol against C. kerstersii strains.…”

Complete genome sequencing of Comamonas kerstersii 8943, a causative agent for peritonitis

“…Shortly after the first report, cases of C. kerstersii related bacteraemia and abdominal infections were documented 3 , 4 . Recently, C. kerstersii were reported to be involved in psoas abscess, pelvic peritonitis and acute perforated appendicitis 5 , 6 . The infections caused by C. kerstersii may be underestimated in previous literatures as the phenotypic methods used for the identification of bacteria cannot provide effective measurement for distinguishing between C. kerstersi and other Comamonas species 2 .…”

First report of Comamonas kerstersii causing urinary tract infection

“… [2] , has recently been observed [3] , [4] . In this sense, the use of new and revolutionary methodologies for bacterial identification in routine laboratory practice, such as matrix-assisted desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) [5] , [6] , could explain the increase in the frequency of isolation of this species reported in the literature in recent years [3] , [4] , [7] , [8] .…”