Unusually exuberant hyperostosis frontalis interna: MRI

Chaljub, Gregory; Johnson, Raleigh F.; Sitton, Clark

doi:10.1007/s002340050703

Cited by 23 publications

(27 citation statements)

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“…The disorder may be associated with a variety of conditions such as seizures, headaches, obesity, diabetes insipidus and excessive hair growth and sex gland disturbances. [2] We report a case of non-syndromic HFI in an 85-year-old female presenting with headache.…”

Section: Introductionmentioning

confidence: 95%

Hyperostosis frontalis interna (HFI): A case report and review of literature

Priyambada¹,

Joshi²,

Ozdemir³

2017

CRIM

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Hyperostosis frontalis interna (HFI) is characterized by excess growth of the frontal bone. Although the exact cause of HFI is not known, it has been found to be associated with increased age, prolonged estrogen stimulation and elevated leptin. Literature shows its association with seizure, dementia, obesity, headache and endocrine abnormalities. HFI may be syndromic and non-syndromic. Timely identification of HFI can prevent unnecessary diagnostic tests. We report a case of non-syndromic HFI in an elderly female who presented with headache.

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Section: Introductionmentioning

confidence: 95%

Hyperostosis frontalis interna (HFI): A case report and review of literature

Priyambada¹,

Joshi²,

Ozdemir³

2017

CRIM

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“…According to Hershkovitz's morphological and histopathological classification, HFI is divided into 4 grades of severity (Table 1). It is usually asymptomatic but, if the bony nodules protrude extensively (bullet-like) or they become too large, the underlying soft tissues, eg, the dura mater and brain, may be compressed (6,7). Some studies underline the presence of brain atrophy in relation with HFI (7,8).…”

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confidence: 96%

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Attanasio

Granziera

Giantin

et al. 2013

The Journal of Clinical Endocrinology & Metabolism

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A case of full penetrance of Morgagni-Stewart-Morel syndrome is reported, presenting many of the clinical features described in the literature. Metabolic and endocrine dysfunctions should be interpreted not only as isolated components of the syndrome, but also as the reason behind its pathogenesis. Endocrine or nutritional disorders may have led to an altered bone metabolism with frontal bone apposition. On the other hand, the severity of our patient's neurological and psychiatric symptoms correlates well with the severity of her hyperostosis frontalis interna and the cortical atrophy.

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“…HFI is fairly common in modern populations, affecting 5-12% of the general population [7]. It has rarely been documented in the archaeological record [34], but with a much lower frequency than in modern groups [35].…”

Section: Discussionmentioning

confidence: 99%

“…HFI may be accompanied by myxoedema [4], acromegaly or prolactinemia [5,6]. Sometimes it is associated with headache and some neuropsychiatric diseases such as epilepsy and dementia [7]. Its association with other pathologic conditions like giant cell arteritis [8] and Klinefelter's syndrome has been reported [9].…”

Section: Introductionmentioning

confidence: 97%

Hyperostosis frontalis interna: An Egyptian case referred to the second dynasty (2890–2650BC) from Tarkhan-Egypt

Shahin

Alhoseiny

Aldali

2014

The Egyptian Rheumatologist

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Aim of the work and case presentation: This article is to present the evidence of hyperostosis frontalis interna (HFI) in a young adult male, approximately (25-26) years old, recovered from a second dynasty site (2890-2650 BC) at Tarkhan in the south of Dahshur-Egypt.HFI is rare in historic populations. It is most commonly found among females with prolonged estrogen stimulation. Males with hormonal disturbances like primary hypogonadism were found to manifest with HFI.Conclusion: This study is a further contribution to the case history of HFI in osteoarcheological studies. Further researches are recommended to have an overview on such an old disease in Egypt.

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Unusually exuberant hyperostosis frontalis interna: MRI

Cited by 23 publications

References 0 publications

Hyperostosis frontalis interna (HFI): A case report and review of literature

Hyperostosis frontalis interna (HFI): A case report and review of literature

Full Penetrance of Morgagni-Stewart-Morel Syndrome in a 75-Year-Old Woman: Case Report and Review of the Literature

Hyperostosis frontalis interna: An Egyptian case referred to the second dynasty (2890–2650BC) from Tarkhan-Egypt

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