Unusually high indoor radon concentrations from a giant rock slide

Ennemoser, O.; Ambach, W.; Brunner, P.; Schneider, P.; Oberaigner, W.; Purtscheller, F.; Stingl, Volkmar; Keller, G.

doi:10.1016/0048-9697(94)90472-3

Cited by 16 publications

(6 citation statements)

References 4 publications

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“…All Rn measurements were performed within the study “Radon und Lungenkrebs im Bezirk Imst/Tirol” by W. Oberaigner et al [ 30 ] in 2002, where long-term measurements in basements and ground floors indoors were used. Ennemoser et al measured concentrations with medians ranging from 361–3750 Bq/m 3 (basements) and 210–1.160 Bq/m 3 (ground floors) in summer and winter, respectively [ 31 ]. The maximum Rn concentration which was measured was 274.000 Bq/m 3 [ 31 ].…”

Section: Methodsmentioning

confidence: 99%

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Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

Gamerith

Kloppenburg

Mildner

et al. 2022

Cancers

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Effective targeted treatment strategies resulted from molecular profiling of lung cancer with distinct prevalent mutation profiles in smokers and non-smokers. Although Rn is the second most important risk factor, data for Rn-dependent driver events are limited. Therefore, a Rn-exposed cohort of lung cancer patients was screened for oncogenic drivers and their survival and genetic profiles were compared with data of the average regional population. Genetic alterations were analysed in 20 Rn-exposed and 22 histologically matched non-Rn exposed LC patients using targeted Next generation sequencing (NGS) and Fluorescence In Situ Hybridization (FISH). Sufficient material and sample quality could be obtained in 14/27 non-exposed versus 17/22 Rn-exposed LC samples. Survival was analysed in comparison to a histologically and stage-matched regional non-exposed lung cancer cohort (n = 51) for hypothesis generating. Median overall survivals were 83.02 months in the Rn-exposed and 38.7 months in the non-exposed lung cancer cohort (p = 0.22). Genetic alterations of both patient cohorts were in high concordance, except for an increase in MET alterations and a decrease in TP53 mutations in the Rn-exposed patients in this small hypothesis generating study.

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Section: Methodsmentioning

confidence: 99%

“…Ennemoser et al measured concentrations with medians ranging from 361–3750 Bq/m 3 (basements) and 210–1.160 Bq/m 3 (ground floors) in summer and winter, respectively [ 31 ]. The maximum Rn concentration which was measured was 274.000 Bq/m 3 [ 31 ].…”

Section: Methodsmentioning

confidence: 99%

Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

Gamerith

Kloppenburg

Mildner

et al. 2022

Cancers

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“…Houses built on the old landslide deposits show high indoor radon levels (Ennemoser et al, 1994). It is important to note that Nepal is one of the most vulnerable zones for earthquakes (Chamlagain, 2009) as well as landslides (Hasegawa et al, 2009).…”

Section: Radonmentioning

confidence: 99%

Environmental radiation – an important concern in the Himalayas (Nepal)

Bhatt

Koirala

Gupta

et al. 2012

Journal of Environmental Radioactivity

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“…The November 1995 Earthquake It was not certain whether radon penetration into the school in on-grade rooms with pipes and conduits directly connecting to porous subsurface rock and gravel increased after the earthquake in November 1995 as a result of subterranean geologic disturbances (13). Nationwide surveillance programs by the Ministry of Environmental Quality indicated that there were no major sustained before-after changes in ambient indoor radon levels throughout the country that were associated with the earthquake, even though findings from the Negev suggested that this event was followed by transient rises in radon concentrations of water from certain ground sources (C Greenblatt, personal communication).…”

Section: Abatement Proceduresmentioning

confidence: 99%

Radon exposures in a Jerusalem public school.

Richter

Ne’eman

Fischer

et al. 1997

Environ Health Perspect

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In December 1995, ambient radon levels exceeding 10,000 Bq/m3 were measured in a basement shelter workroom of a multilevel East Talpiot, Jerusalem, public elementary school (six grades, 600 students). The measurements were taken after cancers (breast and multiple myeloma) were diagnosed in two workers who spent their workdays in basement rooms. The school was located on a hill that geologic maps show to be rich in phosphate deposits, which are a recognized source for radon gas and its daughter products. Levels exceeding 100,000 Bq/m3 were measured at the mouth of a pipe in the basement shelter workroom, the major point of radon entry. The school was closed and charcoal and electret ion chamber detectors were used to carry out repeated 5-day measurements in all rooms in the multilevel building over a period of several months. Radon concentrations were generally higher in rooms in the four levels of the building that were below ground level. There were some ground-level rooms in the building in which levels reached up to 1300 Bq/m3. In rooms above ground level, however, peak levels did not exceed 300 Bq/m3. Exposure control based on sealing and positive pressure ventilation was inadequate. These findings suggested that radon diffused from highly contaminated basement and ground-floor rooms to other areas of the building and that sealing off the source may have led to reaccumulation of radon beneath the building. Later, subslab venting of below-ground radon pockets to the outside air was followed by more sustained reductions in indoor radon levels to levels below 75 Bq/m3. Even so, radon accumulated in certain rooms when the building was closed. This sentinel episode called attention to the need for a national radon policy requiring threshold exposure levels for response and control. A uniform nationwide standard for school buildings below 75 Bq/m3 level was suggested after considering prudent avoidance, the controversies over risk assessment of prolonged low-level exposures in children, and the fact that exposures in most locations in the Talpiot school could be reduced below this level. Proposal of this stringent standard stimulated the search for a strategy of risk control and management based on control at the source. This strategy was more effective and probably more cost effective than one based on suppression of exposure based on sealing and ventilation. Because many Israeli areas and much of the West Bank area of the Palestinian National Authority sit on the same phosphate deposits, regional joint projects for surveillance and control may be indicated.

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Unusually high indoor radon concentrations from a giant rock slide

Cited by 16 publications

References 4 publications

Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

Environmental radiation – an important concern in the Himalayas (Nepal)

Radon exposures in a Jerusalem public school.

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