2018
DOI: 10.1016/j.yexcr.2017.11.006
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Up-regulated miR-548k promotes esophageal squamous cell carcinoma progression via targeting long noncoding RNA-LET

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Cited by 26 publications
(37 citation statements)
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“…Over the past few years, previous studies have reported that non-coding RNAs, including miRNAs and long non-coding RNAs, serve important roles in cancer ( 23 25 ). For example, miR-543 was observed to promote ESCC cell migration, invasion and EMT via targeting phospholipase A2 Group IVA ( 26 ).…”
Section: Discussionmentioning
confidence: 99%
“…Over the past few years, previous studies have reported that non-coding RNAs, including miRNAs and long non-coding RNAs, serve important roles in cancer ( 23 25 ). For example, miR-543 was observed to promote ESCC cell migration, invasion and EMT via targeting phospholipase A2 Group IVA ( 26 ).…”
Section: Discussionmentioning
confidence: 99%
“…For example, miR-146a, miR-133b, miR-106b-3p, miR-219-5p, miR-206, miR-384, miR-455-5p, miR-128, miR-145-3p/5p, miR-10b-3p, miR-874-3p, miR-10a, miR-365, miR-301a, miR-6775-3p, miR-139-5p, miR-516b, miR-449a-5p, miR-125b, miR-433-3p, miR-370, miR-133b, miR-30a-3p/5p, miR-34a, miR-196a, and miR-125b-5p have been shown to act as tumor suppressors by inhibiting ESCC cell proliferation, promoting apoptosis by directly targeting oncogenes, or antagonizing pro-cancer signaling pathways [29,33,35,[40][41][42][43][44][45][46][47][48][49][50][51][52][54][55][56][57][58][60][61][62][63]110,133]. In contrast, pro-oncogenes such as miR-141, miR-21, miR-10b-3p, miR-424, miR-675-3p, miR-543, miR-135, miR-23b-3p, miR-502, miR-21-5p, and miR-548k have been reported to play contrasting roles in promoting cell proliferation or suppressing apoptosis in ESCC [47,[64][65][66][67][68][69][70][71][72][73]. Overall, the roles of miRNAs in cell proliferation and apoptosis can be crucial in ESCC pathogenesis.…”
Section: Non-coding Rnas Regulate Cell Proliferation and Apoptosis Dumentioning
confidence: 99%
“…For example, lncRNA is involved in DNA methylation, chromatin remodeling, and genetic mechanisms of miRNAs, which can affect the development of tumors by disrupting the stability of the genome and affecting the function of the corresponding proteins . LncRNA LET is downregulated in cervical cancer, gastric cancer, and esophageal cancer, and its high expression predicts a good prognosis. In addition, lncRNA LET can inhibit the proliferation and EMT of lung adenocarcinoma cells .…”
Section: Introductionmentioning
confidence: 99%