Update on Gastrointestinal Radiopharmaceuticals and Dosimetry Estimates

Knight, Linda C.

doi:10.1053/j.semnuclmed.2011.11.001

Cited by 26 publications

(29 citation statements)

References 28 publications

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“…The test food used to measure gastric emptying must also meet additional criteria: the food must be in a solid form to stimulate the feeding stage and full physiologic gastric responses, should be palatable to encourage the subject to ingest the entire portion, able to effectively bind a radiolabeled substance that is not absorbed by the gastrointestinal (GI) tract, the portion size must be large enough to enable the differentiation between good and poor GI function and should be easily prepared and inexpensive to administer. 18 Bread, ham and rice have previously been used in conjunction with radiolabeled scrambled or microwaved egg as gastric emptying test foods. 6,19 To best clarify the relationship between masticatory performance and gastric emptying, the same test food should be used for both tests.…”

Section: Introductionmentioning

confidence: 99%

Correlation between the median particle size of chewed frankfurter sausage and almonds during masticatory performance test

Sumonsiri

Thongudomporn

Paphangkorakit

2018

J of Oral Rehabilitation

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The correlation between chewing and gastric function is best reflected when the same food type is used during both tests. We proposed frankfurter sausage as test food for masticatory performance as it can also be used in gastric emptying test. The suitability of frankfurter sausage to determine masticatory performance, however, has never been examined. To examine the correlations between the median particle size of frankfurter sausage and almonds (as standard test food) after different numbers of chewing cycles. Twenty-seven subjects performed masticatory performance tests by chewing 2 types of test foods, that is, a piece of almond or 5-g frankfurter sausage cubes placed in a sealed latex bag, for 5 and 15 chewing cycles. For each individual, right and left sides were tested separately. Chewed samples obtained from both sides were pooled. Median particle sizes were determined using a multiple sieving method. Spearman's rank correlation was used to examine any correlation between median particle sizes of the 2 test foods after 5 and 15 cycles. Median particle sizes after 5 and 15 cycles were 2.04 ± 0.87 and 0.95 ± 0.58 mm for almonds and 4.16 ± 0.19 and 3.73 ± 0.25 mm for frankfurter sausage, respectively. Significant correlations were observed between the median particle size of chewed frankfurter sausage after 15 cycles and that of chewed almonds after 5 and 15 cycles (r = .76, P < .01 and r = .52, P = .01, respectively). Frankfurter sausage chewed for 15 cycles may be suitable for the determination of masticatory performance in conjunction with gastric emptying test.

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Section: Introductionmentioning

confidence: 99%

Correlation between the median particle size of chewed frankfurter sausage and almonds during masticatory performance test

Sumonsiri

Thongudomporn

Paphangkorakit

2018

J of Oral Rehabilitation

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“…99m Tcsulfur colloid has a short half-life of 6 h and when properly cooked is physically bound to certain foods. Because it cannot be absorbed within the gastrointestinal tract, it causes only low radiation exposure (5). With a longer half-life of 67 h, 111 In-diethylenetriaminepentaacetic acid can be used to image gastrointestinal transit that requires 2-3 d, such as colonic transit.…”

Section: General Methodologymentioning

confidence: 99%

Gastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying

Maurer

2016

J. Nucl. Med. Technol.

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CE credit: For CE credit, you can access the test for this article, as well as additional JNMT CE tests, online at https://www.snmmilearningcenter.org. Complete the test online no later than March 2019. Your online test will be scored immediately. You may make 3 attempts to pass the test and must answer 80% of the questions correctly to receive 1.0 CEH (Continuing Education Hour) credit. SNMMI members will have their CEH credit added to their VOICE transcript automatically; nonmembers will be able to print out a CE certificate upon successfully completing the test. The online test is free to SNMMI members; nonmembers must pay $15.00 by credit card when logging onto the website to take the test.Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehensive manner including both quantitative and qualitative analysis of single-and multiple-swallow studies, is clinically useful when expertise in esophageal manometry is not available or not tolerated and when esophageal manometry or barium videofluoroscopy results are equivocal or nondiagnostic. GE scintigraphy has undergone much-needed standardization. Both solid and liquid GE studies play an important role in assessing patients with upper gastrointestinal symptoms. Because measurement of simple total GE is often not sufficient to explain patient symptoms, there is a need to expand the analysis of GE scintigraphy to include the separate roles of the fundus and antrum and to include the complex interactions the stomach has with other organ systems.

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“…Many of these methods are time-consuming, expensive, invasive, and some, such as scintigraphy, may involve significant levels of radiation exposure depending on the radioactive meal and clinical indication [2,4]. Furthermore, there are inter-investigational differences as to which anatomical area of the gut data are obtained from.…”

Section: Introductionmentioning

confidence: 99%

Defining gastrointestinal transit time using video capsule endoscopy: a study of healthy subjects

et al. 2020

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Background and study aims Determining the etiology and location of gastrointestinal motility disorders can be challenging. A range of investigations targeting specific areas of gastrointestinal transit are available, but many provide clinical data for a given gastrointestinal region alone or for non-specific whole gut transit, and are otherwise of limited use. Video capsule endoscopy allows endoscopic visualisation of the entire gastrointestinal tract, and may also provide more specific data for regional transit time abnormalities. Patients and methods Data from video capsules ingested by 71 ambulatory healthy subjects were recorded and analyzed to determine gastric and small bowel transit times in the fasting state. Results Median, and interquartile range (IQR), gastric transit time was 22 (10–48) minutes, and median (IQR) small bowel transit time was 198.5 (157–240.5) minutes. Conclusion These data, for the first time to our knowledge, provide references for gastrointestinal transit times among healthy ambulatory subjects using video capsule endoscopy. This potentially strengthens clinical use of video capsule endoscopy in the investigation of patients with suspected gastrointestinal motility disorders.

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Update on Gastrointestinal Radiopharmaceuticals and Dosimetry Estimates

Cited by 26 publications

References 28 publications

Correlation between the median particle size of chewed frankfurter sausage and almonds during masticatory performance test

Correlation between the median particle size of chewed frankfurter sausage and almonds during masticatory performance test

Gastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying

Defining gastrointestinal transit time using video capsule endoscopy: a study of healthy subjects

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