Background: The prediction of implantable Collamer lens (ICL) vaulting is one of the most important parameters for ICL implantation for safety, aqueous humor circulation, and lens transparency.Methods: This was a retrospective study. A RESCAN 700 was used for intraoperative observation of vaulting. Spectral-domain optical coherence tomography was used for imaging. Results: Finally, 51 patients (102 eyes) were included in the study. Compared with the eyes with normal vaulting, those with high vaulting had higher preoperative diopter values (P=0.039), lower preoperative corrected visual acuity (P=0.006), lower preoperative intraocular pressure (P=0.029), higher preoperative anterior chamber depth (P=0.004), lower preoperative crystalline lens rise (P=0.046), higher ICL spherical equivalent (P=0.030), higher intraoperative vaulting (P<0.001), and lower intraocular pressure at 1 month (P=0.045). The multivariable analysis showed that the only factors independently associated with high vaulting at 1 month after surgery was the intraoperative vaulting value (odds ratio=1.005, 95% confidence interval: 1.002-1.007, P<0.001). The intraoperative and 1-month postoperative vaulting values were correlated (R2=0.562).Conclusions: The RESCAN700 system can be used to perform intraoperative optical coherence tomography to predict the vaulting value at 1 month.