2015
DOI: 10.31480/2330-4871/024
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Updated Mechanisms of Sickle Cell Disease-Associated Chronic pain

Abstract: Sickle cell disease (SCD), a hemoglobinopathy, can cause sickling of red blood cells, resulting in vessel blockage, stroke, anemia, inflammation, and extreme pain. A vast majority of SCD patients experience pain on a chronic basis, and many turn to opioids to provide limited relief. The side effects that come with chronic opioid use push for research into understanding the specific mechanisms of SCD-associated chronic pain. Current advances in SCD-associated pain have focused on alterations in the pain pathway… Show more

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Cited by 12 publications
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References 78 publications
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