Updates in therapeutics for folliculitis decalvans: A systematic review with evidence-based analysis

Rambhia, Pooja H.; Conic, Rosalynn R.Z.; Murad, Aizuri; Atanaskova-Mesinkovska, Natasha; Piliang, Melissa; Bergfeld, Wilma F.

doi:10.1016/j.jaad.2018.07.050

Cited by 46 publications

(62 citation statements)

References 8 publications

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“…One concluded that isotretinoin is the treatment with the largest number of publications, despite the limited response 213 ; the other concluded that the ideal option is the combination of clindamycin and rifampicin, with level of evidence 3. 214 …”

Section: Resultsmentioning

confidence: 99%

Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

Bagatin

Costa

Rocha

et al. 2020

Anais Brasileiros de Dermatologia

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Background Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple mechanisms of action and highly effective in the treatment of acne, despite common adverse events, manageable and dose-dependent. Dose-independent teratogenicity is the most serious. Therefore, off-label prescriptions require strict criteria. Objective To communicate the experience and recommendation of Brazilian dermatologists on oral use of the drug in dermatology. Methods Eight experts from five universities were appointed by the Brazilian Society of Dermatology to develop a consensus on indications for this drug. Through the adapted DELPHI methodology, relevant elements were listed and an extensive analysis of the literature was carried out. The consensus was defined with the approval of at least 70% of the experts. Results With 100% approval from the authors, there was no doubt about the efficacy of oral isotretinoin in the treatment of acne, including as an adjunct in the correction of scars. Common and manageable common adverse events are mucocutaneous in nature. Others, such as growth retardation, abnormal healing, depression, and inflammatory bowel disease have been thoroughly investigated, and there is no evidence of a causal association; they are rare, individual, and should not contraindicate the use of the drug. Regarding unapproved indications, it may represent an option in cases of refractory rosacea, severe seborrheic dermatitis, stabilization of field cancerization with advanced photoaging and, although incipient, frontal fibrosing alopecia. For keratinization disorders, acitretin performs better. In the opinion of the authors, indications for purely esthetic purposes or oil control are not recommended, particularly for women of childbearing age. Conclusions Approved and non-approved indications, efficacy and adverse effects of oral isotretinoin in dermatology were presented and critically evaluated.

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Section: Resultsmentioning

confidence: 99%

Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

Bagatin

Costa

Rocha

et al. 2020

Anais Brasileiros de Dermatologia

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“…The latter rationalizes the use of conventional antimicrobial treatments, such as prolonged antibiotics and dapsone, and of anti-inflammatory drugs as part of the therapeutic armamentarium. 1 However, unclear etiology makes treatment of refractory folliculitis decalvans challenging.…”

Section: Introductionmentioning

confidence: 99%

Successful treatment of refractory folliculitis decalvans with apremilast

et al. 2020

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“…1 Different treatment options exist, nevertheless they are often disappointing and unsatisfactory. 2 We report a recalcitrant case of FD focusing our attention on (1064 nm). [2][3][4] We started at 30 J/cm 2 and then we improved the dose until 80 J/cm 2 These technologies represent noninvasive diagnostic tools and their applications on inflammatory skin diseases have increased in the last years, especially to monitor treatment response in different cutaneous diseases.…”

mentioning

confidence: 99%

“…2 We report a recalcitrant case of FD focusing our attention on (1064 nm). [2][3][4] We started at 30 J/cm 2 and then we improved the dose until 80 J/cm 2 These technologies represent noninvasive diagnostic tools and their applications on inflammatory skin diseases have increased in the last years, especially to monitor treatment response in different cutaneous diseases. In trichologic field, dermoscopy is widely used in dermatologic practice and it is a very helpful tool for assisting in the diagnosis of some forms of folliculitis as FD.…”

mentioning

confidence: 99%

A headstrong case of folliculitis decalvans: Treatment options and evaluation with dermoscopy, reflectance confocal microscopy and optical coherence tomography

Peccerillo

Mandel

Greco

et al. 2020

Dermatologic Therapy

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Updates in therapeutics for folliculitis decalvans: A systematic review with evidence-based analysis

Cited by 46 publications

References 8 publications

Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology

Successful treatment of refractory folliculitis decalvans with apremilast

A headstrong case of folliculitis decalvans: Treatment options and evaluation with dermoscopy, reflectance confocal microscopy and optical coherence tomography

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